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Table 1 Baseline characteristics of the newly diagnosed type 1 diabetes patients with or without G6PD deficiency on admission

From: Glucose-6-Phosphate dehydrogenase deficiency associated hemolysis in a cohort of new onset type 1 diabetes children in Guangdong province, China

 

G6PD non-deficiency

(n = 29)

G6PD deficiency

(n = 27)

t value

P value

Age (y)

7.6 ± 3.5

8.0 ± 5.1

0.17

0.86

Gender (female/male)

13/16

6/21

  

DKA (%)

23 (79%)

22 (81%)

χ2 = 0.04

0.84

HbA1c (%)

12.13 ± 1.61

11.28 ± 2.48

0.91

0.37

FPG/HbA1c

2.25 ± 0.86

2.35 ± 0.75

0.36

0.72

HGB (g/L)

126.12 ± 8.72

119.90 ± 17.30

1.15

0.26

G6PD/6PGD

1.37 ± 0.16

0.36 ± 0.34

9.45

0.00

G6PD gene mutations

 

c.1388G > A (p.Arg493His) (n = 6)

c.1376G > T (p.Arg459Leu) (n = 7)

c.95A > G (p.His32Arg) (n = 4)

c.871G > A (p.Val291Met) (n = 1)

  
  1. DKA diabetic ketoacidosis, HbA1c hemoglobin A1c, FPG fasting plasma glucose, HGB hemoglobin, G6PD glucose-6-phosphate dehydrogenase, 6PGD 6-phosphogluconate dehydrogenase
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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