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Table 1 Demographic characteristics of patients with acromegaly and impaired fasting blood glucose

From: The role of growth hormone and IGF-1 in retinopathy: a prospective study of retinopathy in patients with acromegaly and impaired fasting glucose

 

Acromegaly (n = 91)

Patients with impaired fasting blood glucose (n = 123)

p value

Age (years)

49.9 ± 16.0

59.4 ± 9.7

 < 0.001

Sex (male/female)

42/49

33/90

 < 0.001#

Body height (cm)

167.8 ± 12.1

158.6 ± 7.5

 < 0.001

Body weight (kg)

74.0 ± 17.2

62.3 ± 10.7

 < 0.001

BMI (kg/m2)

26.20 ± 4.62

24.75 ± 3.71

0.013

Systolic BP (mmHg)

128.3 ± 16.5

128.3 ± 14.4

0.989

Diastolic BP (mmHg)

77.6 ± 11.8

76.6 ± 9.2

0.471

Fasting GH (ng/mL)

8.05 ± 16.18

0.78 ± 1.25

 < 0.001

Fasting IGF-1 (ng/mL)

547.0 ± 342.1

146.7 ± 51.4

 < 0.001

Fasting PG (mg/dL)

103.6 ± 20.0

107.8 ± 10.7

0.408

HbA1c (%)

6.22 ± 1.08

6.12 ± 0.48

0.383

Cholesterol (mg/dL)

186.3 ± 27.2

184.4 ± 21.5

0.640

HDL cholesterol (mg/dL)

56.8 ± 26.1

53.2 ± 20.5

0.402

Triglycerides (mg/dL)

111 (86 − 128.5)

109 (79.5 − 171)

0.299*

Creatinine (mg/dL)

0.78 ± 0.41

0.70 ± 0.20

0.087

eGFR (mL/min/1.73 m2)

105.7 ± 32.4

103.0 ± 28.5

0.583

Urine albumin-to-creatine ratio (mg/gCr)

12.7 (4.4 − 70.1)

6.8 (4.85 − 16.75)

0.230*

  1. BP blood pressure, HbA1c glycated hemoglobin, PG plasma glucose, GH growth hormone.
  2. #Fisher’s exact test
  3. *Mann–Whitney U test