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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: LncRNA HOTAIR facilitates high glucose-induced mesangial cell proliferation, fibrosis and oxidative stress in diabetic nephropathy via regulating miR-147a/WNT2B axis

Fig. 3

LncRNA HOTAIR could act as a sponge of miR-147a. A The sequences of lncRNA HOTAIR wt/mut were shown. Dual-luciferase reporter assay (B) and RIP assay (C) were used to assess the interaction between lncRNA HOTAIR and miR-147a. D MiR-147a expression was measured by qRT-PCR in HMC transfected with si-NC or si-lncRNA HOTAIR. E The expression of miR-147a was detected by qRT-PCR in HMC treated with HG or NG. *P < 0.05

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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