Fig.3

Activation of the Wnt/β-catenin pathway induced by high glucose in HMCs. A–F The relative Wnt1, Wnt3, Wnt4, and Wnt5a, β-catenin, and TCF4 mRNA expression detected by qRT-PCR. Total RNA was extracted from treated cells and assessed by qRT-PCR analysis. NG normal glucose, HG high glucose, TRL (50, 100, 200 μM): TRL + high glucose; ^#P < 0.05 versus NG, ^##P < 0.01 versus NG; *P < 0.05 versus HG, **P < 0.01 versus HG.