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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Circular RNA circZNF532 facilitates angiogenesis and inflammation in diabetic retinopathy via regulating miR-1243/CARM1 axis

Fig. 3

circZNF532 served as a molecular sponge for miR-1243. A The predicted binding site between circZNF532 and miR-1243 was displayed by circinteractome. B The overexpression and knockdown efficiencies of miR-1243 were determined using qRT-PCR. C and D The binding relationship between circZNF532 and miR-1243 was validated by dual-luciferase reporter and RIP assays. E The level of miR-1243 in serum from DR patients (n = 23) and healthy controls (n = 23) was examined by qRT-PCR. F The expression of miR-1243 was detected by qRT-PCR in hRMECs stimulated with NG or HG for different times. G The level of miR-1243 was measured using qRT-PCR in hRMECs transfected with si-circZNF532 or si-NC. *P < 0.05

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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