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Table 1 Demographics and clinical characteristics

From: AK098656: a new biomarker of coronary stenosis severity in hypertensive and coronary heart disease patients

Characters

Healthy controls

(n = 27)

CHD

(n = 25)

CHD + hDM

(n = 24)

CHD + hHTN

(n = 41)

CHD + hDM + hHTN

(n = 27)

Age, years

48.9 ± 14.9

62.2 ± 13.8

63.0 ± 10.4

62.4 ± 11.4

68.3 ± 11.3

Gender, M/F

13/14

19/6

13/11

29/12

15/12

Heart rate, beats/min

60.7 ± 41.9

73.8 ± 15.6

81.9 ± 17.2

73.8 ± 17.4

81.9 ± 21.0

Hypertension history

No

No

No

Yes

Yes

Drug use

     

 Aspirin, n (%)

3 (11.1%)

22 (88%)

24 (100%)

33 (80.5%)

21 (77.8%)

 Clopidogrel, (%)

0

9 (36%)

15 (62.5%)

18 (43.9%)

15 (55.6%)

 Statin, n (%)

0

17 (68%)

23 (95.8%)

35 (85.4%)

20 (74.1%)

 Calcium antagonist, (%)

4 (14.8%)

2 (8%)

2 (8.3%)

17 (41.5%)

13 (48.1%)

 β-blocker, n (%)

3 (11.1%)

13 (52%)

16 (66.7%)

24 (58.5)

12 (44.4%)

Total cholesterol, mmol/L (SCHO)

4.48 ± 0.88

4.78 ± 1.21

4.64 ± 1.09

4.21 ± 1.12

3.93 ± 0.89

Total trigly (STG)

1.19 ± 0.71

1.62 ± 0.87

1.94 ± 1.28

1.50 ± 0.80

1.65 ± 0.97

HDL cholesterol, mmol/L (SHDL)

1.37 ± 0.39

1.14 ± 0.25

1.06 ± 0.24

1.09 ± 0.23

1.12 ± 0.24

LDL cholesterol, mmol/L (SLDL)

2.67 ± 0.67

3.09 ± 0.84

3.15 ± 0.83

2.73 ± 0.90

2.42 ± 0.74

Fasting glucose, mmol/L (SFBG)

5.49 ± 1.20

5.55 ± 0.99

8.54 ± 3.37

5.77 ± 1.37

8.98 ± 2.99

Insulin

10.96 ± 6.69

14.75 ± 14.41

18.09 ± 20.80

17.83 ± 16.40

24.00 ± 27.50

C-peptide

2.35 ± 0.69

3.76 ± 12.71

3.78 ± 4.01

3.87 ± 2.08

4.25 ± 3.07

Coronary stenosis

     

 Mild

–

4

2

4

3

 Moderate

–

7

4

14

5

 Severe

–

8

8

12

8

 Not available

–

6

10

11

11

  1. Data are presented as mean value ± standard deviation or count (%). CHD: coronary heart disease; hDM: human diabetes mellitus; hHTN: human hypertension