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Table 1 Demographics and clinical characteristics

From: AK098656: a new biomarker of coronary stenosis severity in hypertensive and coronary heart disease patients

Characters Healthy controls
(n = 27)
CHD
(n = 25)
CHD + hDM
(n = 24)
CHD + hHTN
(n = 41)
CHD + hDM + hHTN
(n = 27)
Age, years 48.9 ± 14.9 62.2 ± 13.8 63.0 ± 10.4 62.4 ± 11.4 68.3 ± 11.3
Gender, M/F 13/14 19/6 13/11 29/12 15/12
Heart rate, beats/min 60.7 ± 41.9 73.8 ± 15.6 81.9 ± 17.2 73.8 ± 17.4 81.9 ± 21.0
Hypertension history No No No Yes Yes
Drug use      
 Aspirin, n (%) 3 (11.1%) 22 (88%) 24 (100%) 33 (80.5%) 21 (77.8%)
 Clopidogrel, (%) 0 9 (36%) 15 (62.5%) 18 (43.9%) 15 (55.6%)
 Statin, n (%) 0 17 (68%) 23 (95.8%) 35 (85.4%) 20 (74.1%)
 Calcium antagonist, (%) 4 (14.8%) 2 (8%) 2 (8.3%) 17 (41.5%) 13 (48.1%)
 β-blocker, n (%) 3 (11.1%) 13 (52%) 16 (66.7%) 24 (58.5) 12 (44.4%)
Total cholesterol, mmol/L (SCHO) 4.48 ± 0.88 4.78 ± 1.21 4.64 ± 1.09 4.21 ± 1.12 3.93 ± 0.89
Total trigly (STG) 1.19 ± 0.71 1.62 ± 0.87 1.94 ± 1.28 1.50 ± 0.80 1.65 ± 0.97
HDL cholesterol, mmol/L (SHDL) 1.37 ± 0.39 1.14 ± 0.25 1.06 ± 0.24 1.09 ± 0.23 1.12 ± 0.24
LDL cholesterol, mmol/L (SLDL) 2.67 ± 0.67 3.09 ± 0.84 3.15 ± 0.83 2.73 ± 0.90 2.42 ± 0.74
Fasting glucose, mmol/L (SFBG) 5.49 ± 1.20 5.55 ± 0.99 8.54 ± 3.37 5.77 ± 1.37 8.98 ± 2.99
Insulin 10.96 ± 6.69 14.75 ± 14.41 18.09 ± 20.80 17.83 ± 16.40 24.00 ± 27.50
C-peptide 2.35 ± 0.69 3.76 ± 12.71 3.78 ± 4.01 3.87 ± 2.08 4.25 ± 3.07
Coronary stenosis      
 Mild 4 2 4 3
 Moderate 7 4 14 5
 Severe 8 8 12 8
 Not available 6 10 11 11
  1. Data are presented as mean value ± standard deviation or count (%). CHD: coronary heart disease; hDM: human diabetes mellitus; hHTN: human hypertension