Characters | Healthy controls (n = 27) | CHD (n = 25) | CHD + hDM (n = 24) | CHD + hHTN (n = 41) | CHD + hDM + hHTN (n = 27) |
---|---|---|---|---|---|
Age, years | 48.9 ± 14.9 | 62.2 ± 13.8 | 63.0 ± 10.4 | 62.4 ± 11.4 | 68.3 ± 11.3 |
Gender, M/F | 13/14 | 19/6 | 13/11 | 29/12 | 15/12 |
Heart rate, beats/min | 60.7 ± 41.9 | 73.8 ± 15.6 | 81.9 ± 17.2 | 73.8 ± 17.4 | 81.9 ± 21.0 |
Hypertension history | No | No | No | Yes | Yes |
Drug use | Â | Â | Â | Â | Â |
 Aspirin, n (%) | 3 (11.1%) | 22 (88%) | 24 (100%) | 33 (80.5%) | 21 (77.8%) |
 Clopidogrel, (%) | 0 | 9 (36%) | 15 (62.5%) | 18 (43.9%) | 15 (55.6%) |
 Statin, n (%) | 0 | 17 (68%) | 23 (95.8%) | 35 (85.4%) | 20 (74.1%) |
 Calcium antagonist, (%) | 4 (14.8%) | 2 (8%) | 2 (8.3%) | 17 (41.5%) | 13 (48.1%) |
 β-blocker, n (%) | 3 (11.1%) | 13 (52%) | 16 (66.7%) | 24 (58.5) | 12 (44.4%) |
Total cholesterol, mmol/L (SCHO) | 4.48 ± 0.88 | 4.78 ± 1.21 | 4.64 ± 1.09 | 4.21 ± 1.12 | 3.93 ± 0.89 |
Total trigly (STG) | 1.19 ± 0.71 | 1.62 ± 0.87 | 1.94 ± 1.28 | 1.50 ± 0.80 | 1.65 ± 0.97 |
HDL cholesterol, mmol/L (SHDL) | 1.37 ± 0.39 | 1.14 ± 0.25 | 1.06 ± 0.24 | 1.09 ± 0.23 | 1.12 ± 0.24 |
LDL cholesterol, mmol/L (SLDL) | 2.67 ± 0.67 | 3.09 ± 0.84 | 3.15 ± 0.83 | 2.73 ± 0.90 | 2.42 ± 0.74 |
Fasting glucose, mmol/L (SFBG) | 5.49 ± 1.20 | 5.55 ± 0.99 | 8.54 ± 3.37 | 5.77 ± 1.37 | 8.98 ± 2.99 |
Insulin | 10.96 ± 6.69 | 14.75 ± 14.41 | 18.09 ± 20.80 | 17.83 ± 16.40 | 24.00 ± 27.50 |
C-peptide | 2.35 ± 0.69 | 3.76 ± 12.71 | 3.78 ± 4.01 | 3.87 ± 2.08 | 4.25 ± 3.07 |
Coronary stenosis | Â | Â | Â | Â | Â |
 Mild | – | 4 | 2 | 4 | 3 |
 Moderate | – | 7 | 4 | 14 | 5 |
 Severe | – | 8 | 8 | 12 | 8 |
 Not available | – | 6 | 10 | 11 | 11 |