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Table 8 Results of SOCS3 and JAK2 gene haplotype analysis

From: Association analysis of SOCS3, JAK2 and STAT3 gene polymorphisms and genetic susceptibility to type 2 diabetes mellitus in Chinese population

 

Haplotype

T2DM (%)

NC (%)

P

OR (95% CI)

S1

AG

165 (15.8)

159 (14.5)

0.414

0.91 (0.72–1.15)

S2

AT

294 (28.2)

271 (24.7)

0.069

0.84 (0.69–1.01)

S3

GG

101 (9.7)

35 (3.2)

 < 0.001

0.31 (0.21–0.46)

S4

GT

484 (46.3)

631 (57.6)

 < 0.001

1.57 (1.33–1.87)

J1

AG

254 (27.0)

304 (27.7)

0.707

1.04 (0.85–1.26)

J2

AG

32 (3.4)

98 (9.0)

 < 0.001

2.85 (1.89–4.29)

J3

GC

109 (11.5)

36 (3.3)

 < 0.001

0.26 (0.18–0.39)

J4

GG

547 (58.1)

656 (58.1)

0.406

1.08 (0.90–1.29)