Skip to main content

Table 6 Comparison of genetic models between T2DM and NC

From: Association analysis of SOCS3, JAK2 and STAT3 gene polymorphisms and genetic susceptibility to type 2 diabetes mellitus in Chinese population

SNPs Additive model Dominant model Recessive model
P OR (95% CI) adP adOR (95% CI) P OR (95% CI) adP adOR (95% CI) P OR (95% CI) adP adOR (95% CI)
rs4969168 0.044 0.84 (0.70–1.00) 0.008 0.77 (0.63–0.93) 0.062 0.79 (0.61–1.01) 0.016 0.70 (0.53–0.94) 0.171 2.00 (1.42–2.81) 0.064 0.71 (0.49–1.02)
rs2280148  < 0.01 0.65 (0.53–0.79)  < 0.01 0.61 (0.48–0.77)  < 0.01 0.61 (0.48–0.77)  < 0.01 0.56 (0.43–0.74) 0.023 0.40 (0.27–0.58) 0.048 0.51 (0.26–1.00)
rs10974914 0.007 1.25 (1.06–1.48) 0.014 1.26 (1.05–1.52) 0.316 1.13 (0.89–1.42) 0.501 1.09 (0.84–1.42)  < 0.01 1.74 (1.23–2.46)  < 0.01 2.13 (1.47–3.10)
rs10815157  < 0.01 0.73 (0.61–0.87) 0.018 0.79 (0.64–0.96) 0.151 0.83 (0.65–1.07) 0.482 0.90 (0.68–1.20)  < 0.01 0.87 (0.66–1.14)  < 0.01 0.46 (0.30–0.69)
rs1053005 0.311 1.10 (0.92–1.31) 0.119 1.18 (0.96–1.45) 0.375 0.96 (0.74–1.23) 0.865 0.98 (0.73–1.30) 0.002 0.80 (0.58–1.10) 0.002 1.91 (1.28–2.86)