Fig. 2From: Histone lysine-specific demethylase 1 induced renal fibrosis via decreasing sirtuin 3 expression and activating TGF-β1/Smad3 pathway in diabetic nephropathyKnockdown of LSD1 decreases the expression of serum biochemical markers. The fasting blood glucose (FBG) was measured through blood from tail tip. The urine output in 24 h was measured. The urinary protein (24 h), serum creatinine and blood urea nitrogen (BUN) were determined by ELISA kit, respectively. The urinary albumin-to-creatinine ratio (UACR) was calculated. Each group contained 10 rats. **p < 0.01 vs. Sham. ##p < 0.01 vs. STZ + Ad-shLSD1Back to article page