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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Histone lysine-specific demethylase 1 induced renal fibrosis via decreasing sirtuin 3 expression and activating TGF-β1/Smad3 pathway in diabetic nephropathy

Fig. 2

Knockdown of LSD1 decreases the expression of serum biochemical markers. The fasting blood glucose (FBG) was measured through blood from tail tip. The urine output in 24 h was measured. The urinary protein (24 h), serum creatinine and blood urea nitrogen (BUN) were determined by ELISA kit, respectively. The urinary albumin-to-creatinine ratio (UACR) was calculated. Each group contained 10 rats. **p < 0.01 vs. Sham. ##p < 0.01 vs. STZ + Ad-shLSD1

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