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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: Histone lysine-specific demethylase 1 induced renal fibrosis via decreasing sirtuin 3 expression and activating TGF-β1/Smad3 pathway in diabetic nephropathy

Fig. 1

Knockdown of LSD1 alleviates STZ-induced renal injury. The STZ-induced DN rats were treated with Ad-shNC or Ad-shLSD1. A HE staining of the renal tissues of rats in each group indicated LSD1 alleviates STZ-induced renal injury (bar = 100 μm). B The LSD1 expression was detected by immunofluorescence assay (bar = 100 μm). Each group contained 10 rats. **p < 0.01 vs. Sham. ##p < 0.01 vs. STZ + Ad-shLSD1

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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