Gradual increasing dyslipidemia in treatment-naive male patients with human immunodeficiency virus and treated with tenofovir plus lamivudine plus efavirenz for 3 years

Table 2 Spearman correlation analysis between lipid metabolism parameters and age, anthropometric parameters, and immunological and virological indicators (n = 61)

Variable	TC (mmol/L)		TG (mmol/L)		HDL-c (mmol/L)		LDL-c (mmol/L)		UA (µmol/L)
Variable	r	p	r	p	r	p	r	p	r	p
NAFLD (1 = without, 2 = with)	0.357	0.002	0.353	0.003	− 0.255	0.033	0.251	0.038	0.320	<0.0001
Age (year)	0.304	< 0.0001	0.164	0.004			0.226	<0.0001	− 0.151	<0.0001
Body weight (kg)	0.243	0.013	0.241	0.014	− 0.413	<0.0001	0.341	<0.0001	0.338	<0.0001
Body mass index (kg/m²)	0.343	0.001	0.236	0.021			0.418	<0.0001
Body fat percentage (%)	0.318	0.002	0.460	<0.0001	− 0.238	0.020	0.283	0.006
Body fat weight (kg)	0.312	0.002	0.390	<0.0001	− 0.338	0.001	0.326	0.001
Body nonfat weight (kg)					− 0.378	<0.0001	0.319	0.002	0.377	<0.0001
CD3+CD4+ count (cells/µl)									0.161	<0.0001
Virus load (IU/ml)									0.306	0.001
Follow-up duration	0.192	<0.0001			0.281	<0.0001

NAFLD, nonalcoholic fatty liver disease. TG, triglyceride. TC, total cholesterol. LDL-c, low-density lipoprotein cholesterol. HDL-c, high-density lipoprotein cholesterol. UA, uric acid

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