Adiponectin gene polymorphisms and risk of type 2 diabetes: an updated evidence for meta-analysis

Alimi, Mahrokh; Goodarzi, Mohammad Taghi; Nekoei, Mehdi

doi:10.1186/s13098-021-00749-x

Diabetology & Metabolic Syndrome

Table 2 The baseline information of studies included for assessment of association between SNP + 276 (rs1501299) and risk of type 2 diabetes

From: Adiponectin gene polymorphisms and risk of type 2 diabetes: an updated evidence for meta-analysis

Author's name	Country	Study design	Sex ratio of case (M/F)	Genotyping	Ethnicity	Target population	Sample size (Diabetes)	Sample size (Control)	Case			Control			P-value for HWE	NOS score
									TT	GT	GG	TT	GT	GG	P-value for HWE
Hara et al. [18]	Japan	Case–control	267/117	SNaPshot ddNTP	Asian	Japanese	384	480	18	142	224	41	203	236	0.08	8
Menzaghi et al. [40]	Italy	Case–control	167/143	PCR-hydridization	Caucasian	Italian Caucasian	310	304	28	124	158	27	117	160	0.7	8
Populaire et al. [39]	Japan	Case–control	82/82	PCR–RFLP	Asian	Japanese	164	177	22	55	87	18	80	79	0.12	9
Gu et al. [20]	Sweden	Case–control	56/50	DASH	Caucasian	Swedish Caucasians	106	497	101	46	50	42	206	249	0.004	8
Fumeron et al. [41]	France	Cohort	150/79	fluorogenic	Caucasian	French Caucasian	229	3072	15	64	97	305	1773	2419	0.67	7
Hu et al. [21]	USA	Nested Case–control	642F	TaqMan	Caucasian	Caucasians	642	995	54	266	322	73	399	523	0.07	9
Gibson et al. [22]	UK	Case–control	390/422	Ampli-Fluor	Caucasian	French Caucasian	701	893	51	276	374	75	368	450	0.0003	7
de Courten et al. [42]	USA	Cohort	496/584	PCR–RFLP	Indian	Pima Indians	1080	1080	26	200	371	24	133	249	1.2	7
Lee et al. [43]	Korea	Case–control	237/256	SNaPshot ddNTP	Korean	Korean population	493	427	38	231	224	35	167	225	0.26	6
Sanchez et al. [44]	Finland	Cross-sectional	356/391	PCR-SnaPshot	Spanish	Spanish	747	747	5	35	24	39	231	260	1.61	6
Vasseur et al. [23]	France	Case–control	115/329	LightCycler technology	Caucasians	French Caucasians	444	535	23	89	97	23	93	132	0.34	8
Tso et al. [24]	Hong Kong	Cohort	76/82	PCR–RFLP	Chinese	Chinese	137	125	17	59	82	15	40	49	2	7
Gable et al. [26]	UK	Cohort	169 M	TaqMan	Caucasians	European Caucasian	169	2767	10	59	87	175	1015	1470	0.92	6
Yang et al. [45]	China	Case–control	75/137	SEQUENOM genotyping system	Chinese	Chinese	637	801	42	206	191	661	408	499	2.04	8
Hivert et al. [29]	USA	Cohort	515/580	Mass spectroscopy	White	White	282	1448	15	61	100	111	641	864	0.28	7
Magdalena et al. [46]	Poland	Case–control	217/278	PCR–RFLP	Caucasian	Polish Caucasian	495	435	11	131	353	11	150	274	0.024	9
Mohammadzadeh et al. [47]	Iran	Case–control	26/24	PCR–RFLP	Iranian	Iranian	50	52	2	19	29	4	21	27	0.41	8
Wang et al. [32]	China	Case–control	394/591	TaqMan	Han	Han Chinese	985	1050	66	397	451	72	398	496	0.41	7
Chiodini et al. [33]	Italy	Cohort	285/218	TaqMan	Italians	Italians	503	503	52	206	245	66	198	239	0.02	9
Alimi et al. [11]	Iran	Case–control	57/43	Tetra ARMS-PCR	Iranian	Iranian	100	110	8	45	47	8	44	58	0.3	6

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ISSN: 1758-5996

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