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Table 3 Anthropometric and cardiometabolic risk indicators according to the Sex-specific thresholds of the fat-to-muscle ratio

From: The association between fat-to-muscle ratio and metabolic disorders in type 2 diabetes

Variable

Low-FMR group

(n = 109)

High-FMR group

(n = 252)

P value

Weight (kg)

58.5 ± 9.8

70.1 ± 11.6

 < 0.001

BMI (kg/m2)

21.3 ± 2.5

26.1 ± 3.2

 < 0.001

Waist circumference (cm)

84.2 ± 8.3

95.4 ± 8.8

 < 0.001

Fat mass (kg)

11.6 ± 3.8

20.9 ± 5.4

 < 0.001

Muscle mass (kg)

43.4 ± 8.2

45.2 ± 8.2

0.059

Body fat percentage (%)

19.9 ± 6.1

29.8 ± 5.2

 < 0.001

Systolic blood pressure (mmHg)

127.1 ± 17.0

132.9 ± 19.6

0.005

Diastolic blood pressure (mmHg)

75.0 ± 10.7

77.9 ± 12.5

0.039

Total cholesterol (mmol/L)

4.9 ± 1.3

5.1 ± 1.5

0.212

Triglycerides (mmol/L)

1.2 (0.9–1.8)

1.9 (1.3–2.9)

 < 0.001

HDL-cholesterol (mmol/L)

1.2 ± 0.3

1.0 ± 0.3

 < 0.001

LDL-cholesterol (mmol/L)

2.9 ± 1.0

3.0 ± 1.0

0.594

TG/HDL ratio

1.0 (0.7–1.7)

1.8 (1.1–3.1)

 < 0.001

HOMA2-IR

1.8 ± 1.1

2.6 ± 1.5

 < 0.001

Hypertension (n, %)

43 (39.4%)

176 (69.8%)

 < 0.001

Fatty liver disease (n, %)

39 (36.8%)

179 (74.6%)

 < 0.001

Abdominal obesity (n, %)

37 (33.9%)

210 (83.3%)

 < 0.001

Hypertriglyceridemia (n, %)

31 (28.4%)

145 (57.5%)

 < 0.001

Low HDL-cholesterol (n, %)

33 (30.3%)

142 (56.3%)

 < 0.001

Metabolic syndrome (n, %)

41 (37.6%)

219 (86.9%)

 < 0.001

  1. The thresholds of fat-to-muscle ratio were derived from ROC analysis, where FMR > 0.296 in male or > 0.465 in female was classified as high-FMR
  2. FMR fat-to-muscle ratio