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Table 1 Baseline characteristics of participants (N = 8151)

From: Nonlinear relationship between HbA1c and coronary artery calcium score progression: a secondary analysis based on a retrospective cohort study

 

Coronary artery calcium score progression

 

No

Yes

P-value

N

3284

4867

 

HbA1c, mean ± sd, (%)

5.51 ± 0.62

5.73 ± 0.82

 < 0.001

Sex, (n, %)

  

0.012

 Male

2956 (90.01%)

4460 (91.64%)

 

 Female

328 (9.99%)

407 (8.36%)

 

Age group, (n, %)

  

 < 0.001

 < 65

3133 (95.40%)

4198 (86.25%)

 

 >  = 65

151 (4.60%)

669 (13.75%)

 

Duration, mean ± sd, (year)

3.69 ± 2.03

4.00 ± 2.23

 < 0.001

BMI, mean ± sd, (kg/m2)

24.42 ± 2.48

24.94 ± 2.60

 < 0.001

Height, mean ± sd, (cm)

169.84 ± 6.77

169.16 ± 6.59

 < 0.001

Weight, mean ± sd, (kg)

70.61 ± 9.37

71.49 ± 9.51

 < 0.001

SBP, mean ± sd, (mmHg)

117.59 ± 15.12

120.59 ± 15.83

 < 0.001

DBP, mean ± sd, (mmHg)

74.92 ± 10.50

76.23 ± 10.52

 < 0.001

TC, mean ± sd, (mg/dL)

197.69 ± 33.04

199.18 ± 34.87

0.085

LDL-C, mean ± sd, (mg/dL)

127.61 ± 30.05

128.77 ± 31.55

0.100

HDL-C, mean ± sd, (mg/dL)

52.60 ± 12.89

51.36 ± 12.51

 < 0.001

Triglycerides, median (Q1-Q3), (mg/dL)

121.00 (86.00–171.00)

128.00 (93.00–181.00)

 < 0.001

Smoking status, (n, %)

  

 < 0.001

 Never

960 (34.35%)

1201 (28.28%)

 

 Past smoker

998 (35.71%)

1755 (41.32%)

 

 Current smoker

837 (29.95%)

1291 (30.40%)

 

Alcohol consumption, (n, %)

  

0.012

 Never

399 (13.00%)

693 (14.98%)

 

 Past drinker

42 (1.37%)

85 (1.84%)

 

 Current drinker

2629 (85.64%)

3848 (83.18%)

 

Reflux esophagitis status, (n, %)

  

0.001

 Negative

2938 (89.46%)

4237 (87.06%)

 

 Positive

346 (10.54%)

630 (12.94%)

 

Hypertension, n (%)

  

 < 0.001

 Negative

3097 (94.31%)

4423 (90.88%)

 

 Positive

346 (10.54%)

630 (12.94%)

 

Diabetes, n (%)

  

 < 0.001

 Negative

3214 (97.87%)

4698 (96.53%)

 

 Positive

70 (2.13%)

169 (3.47%)

 

Dyslipidemia, n (%)

  

0.012

 Negative

3095 (94.24%)

4518 (92.83%)

 

 Positive

189 (5.76%)

349 (7.17%)

 

Ischemic heart disease, n (%)

  

0.015

 Negative

3279 (99.85%)

4844 (99.53%)

 

 Positive

5 (0.15%)

23 (0.47%)

 

Cerebrovascular disease n (%)

  

1.000

 Negative

3281 (99.91%)

4862 (99.90%)

 

 Positive

3 (0.09%)

5 (0.10%)

 
  1. HbA1c glycated hemoglobin, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, CAC-P coronary artery calcium score progression. The data presented are the means ± standard deviations, median (Q1–Q3) or numbers (percentages)