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Table 1 Baseline characteristics comparison between NAFLD patients and control subjects

From: Association of anti-oxidative capacity of HDL with subclinical atherosclerosis in subjects with and without non-alcoholic fatty liver disease

Parameter

Control (n  =  92)

NAFLD (n  =  51)

P value

Age (years)

59.0 (55.0–66.0)

56.0 (54.0–61.0)

0.273

BMI (kg/m2)

24.8 ± 3.6

29.3 ± 3.4

< 0.001

WC (cm)

93.2 ± 11.1

103.6 ± 9.6

< 0.001

WHR

0.97 (0.92–1.00)

0.98 (0.94–1.03)

0.002

Weight (kg)

68.7 (61.0–79.5)

80.7 (73.5–89.0)

< 0.001

TC (mg/dL)

205.5 ± 39.4

207.3 ± 37.0

0.779

LDL-C (mg/dL)

121.6 ± 33.7

124.6 ± 28.7

0.594

HDL-C (mg/dL)

57.4 ± 12.5

51.9 ± 11.1

0.007

TG (mg/dL)

112.0 (82.0–158.0)

148.5 (112.5–186.0)

0.016

Systolic blood pressure (mmHg)

131.5 ± 21.3

144.9 ± 23.7

0.001

Diastolic blood pressure (mmHg)

79.9 ± 11.0

86.8 ± 12.4

0.001

FBG (mg/dL)

92.71 ± 9.00

99.57 ± 11.21

< 0.001

Visceral fat (%)

46.5 ± 20.7

70.2 ± 18.0

< 0.001

AST (U/L)

18.5 (15.0–22.0)

22.0 (19.5–27.0)

< 0.001

ALT (U/L)

15.5 (11.0–22.0)

31.5 (23.0–41.0)

< 0.001

GGT (U/L)

22.37 (17.40–29.10)

28.65 (23.53–38.50)

< 0.001

LS (kPa)

3.8 (3.3–4.3)

5.0 (4.2–6.6)

< 0.001

cIMT (mm)

0.8 (0.75–0.87)

0.81 (0.74–0.91)

0.863

HOI

0.92 ± 0.19

0.95 ± 0.24

0.405

HOI  ≥ 1 frequency (%)

33.69

41.17

0.468

SOD (U/mg protein)

10.7 ± 1.5

8.6 ± 2.4

< 0.001

MDA (µM)

33.2 (25.0–42.3)

34.0 (30.4–47.7)

0.771

PON1 (U/L)

24.4 (17.7–31.1)

42.2 (27.7–52.2)

< 0.001

Hypertension (%)

27.90

47.36

0.021

  1. Comparisons between groups were performed using Independent Student’s t test or Mann–Whitney U test as appropriate. Continuous data are expressed as mean  ±  standard deviation (SD) or median and (interquartile range), categorical data as percentages
  2. BMI body mass index; WC waist circumference; WHR waist to hip ratio; TC total cholesterol; LDL-C low density lipoprotein cholesterol; HDL-C high density lipoprotein cholesterol; TG triglycerides; AST aspartate amino transferase; ALT alanine amino transferase; GGT gamma glutamyl transferase; LS liver stiffness; cIMT carotid intima-media thickness; MDA malondialdehyde; PON1 paraoxonase 1; SOD superoxide dismutase; HOI HDL oxidative index
  3. P  <  0.05 was considered statistically significant