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Table 1 Clinical and demographic characteristics of individuals in different study groups

From: Klotho and SIRT1 changes from pre-diabetes to diabetes and pre-hypertension to hypertension

 

CTL

Pre-DM

DM

Pre-HTN

HTN

DM + HTN

Number

40

41

40

41

41

26

 Sex (male)

20 (50%)

20 (48.8%)

16 (40%)

21 (51.2%)

20 (48.8%)

13 (50%)

Age (years)

58.05 ± 10.7

58.9 ± 10.5

58.7 ± 11.8

58.4 ± 10.2

58.6 ± 10.3

58.5 ± 10.4

BMI (Kg/m2)

25.7 ± 3.3

25.9 ± 2.9

25.1 ± 3.5

24.9 ± 3.2

25.7 ± 3.1

26.8 ± 2.5

FBS (mg/dl)

86.2 ± 7.6

108.7 ± 7.2*

166.7 ± 48.3*

86.5 ± 7.0

85.9 ± 6.7

170.6 ± 45.32*

HbA1C (%)

NM

NM

7.46 ± 2.5

NM

NM

7.5 ± 2.1

SBP (mmHg)

106.5 ± 6.3

116.7 ± 13.6*

101.3 ± 9.9

129.7 ± 4.6*

153.9 ± 16.7*

141.3 ± 14.7*

DBP (mmHg)

65.5 ± 6.5

72.7 ± 5.7*

67.0 ± 6.1

75.0 ± 6.7*

95.9 ± 11.0*

87.9 ± 7.8*

MAP (mmHg)

79.2 ± 5.7

87.4 ± 5.3

78.4 ± 6.7

93.3 ± 5.3

115.3 ± 11.0*

105.7 ± 7.1*

Cholesterol (mg/dl)

185.2 ± 30.4

185.3 ± 33.6

186.4 ± 31.8

187.0 ± 30.3

192.3 ± 30.8

187.5 ± 34.2

Triglyceride(mg/dl)

119.2 ± 89.7

143.6 ± 88.0

146.8 ± 101.7

111.0 ± 61.4

140.4 ± 72.4

131.9 ± 65.9

HDL (mg/dl)

42.9 ± 11.7

43.0 ± 11.2

47.1 ± 11.3

46.9 ± 11.8

49.9 ± 11.9

51.9 ± 11.6

LDL (mg/dl)

119.7 ± 23.3

113.7 ± 31.4

111.7 ± 30.7

117.9 ± 29.1

115.1 ± 25.0

114.2 ± 26.3

  1. Data are expressed as mean  ±  SD or median (interquartile range)
  2. NM not measured; CTL control; Pre-DM pre-diabetes; DM diabetes mellitus; Pre-HTN pre-hypertension; HTN hypertension
  3. *P  <  0.01 vs control