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Table 3 HOMA-β and HOMA-IR in Sitagliptin group and Control group

From: Ten-year follow-up of sitagliptin treatment in patients with type 2 diabetes mellitus

 

Sitagliptin group (n = 17)

Month of Study

0

6

12

24

48

72

96

120

HOMA-β

15.6 (8.81)

13.1 (8.15)

19.5 (10.5)

20.3 (7.41)*

24.6 (8.60)*

28.12 (8.91)*

31.2 (12.2)*

31.4 (10.41)*

HOMA-IR

1.15 (0.74)

1.14 (0.63)

1.14 (0.60)

1.12 (0.59)

1.15 (0.61)

1.18 (0.55)

1.14 (0.61)

1.15 (0.54)

 

Control group (n = 9)

Month of Study

0

6

12

24

48

72

96

120

HOMA-β

21.6 (18.7)

22.0 (16.6)

19.5 (13.1)

22.4 (18.7)

20.9 (21.2)

21.1 (4.2)

24.2 (18.5)

23.2 (18.4)

HOMA-IR

1.14 (0.81)

1.36 (0.67)

1.27 (0.61)

1.41 (0.74)

1.29 (0.76)

1.21 (0.66)

1.22 (0.52)

1.17 (0.50)

  1. Values are shown as means ± SD in parentheses
  2. HOMA-β, homeostatic model assessment of β cell function, HOMA-IR homeostatic model assessment of insulin resistance
  3. *Intragroup comparison: p < 0.05 (paired t test)