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Table 1 Clinical parameters in Sitagliptingroup and Control group

From: Ten-year follow-up of sitagliptin treatment in patients with type 2 diabetes mellitus

  Sitagliptin group (n = 17)
Month of Study 0 6 12 24 48 72 96 120
FBG(mg/dl) 142 (38) 130 (19)* 136 (24)* 129 (22)* 128 (10)* 128 (12)* 112 (18)* 111 (14)*
HbA1c (%) 6.9 (0.92) 6.3 (0.70)* 6.6 (0.62)* 6.4(0.66)* 6.3 (0.42)* 6.3 (0.71)* 6.4 (0.20)* 6.3 (0.16)*
BMI 22.4 (3.4) 22.6 (3.3) 22.5 (3.1) 22.5 (3.7) 22.3 (3.2) 22.7 (3.2) 22.4 (3.6) 22.4 (3.7)
hsCRP(ng/ml) 452 (308) 260 (131)* 275 (189*) 190 (136)* 171 (139)* 160 (122)* 171 (77) * 162 (69)*
ACR(mg/gCr) 205 (390) 131 (263) 97 (286) 50 (165) 40 (102) 39 (109) 54 (130) 41 (105)
SBP (mmHg) 140 (18) 129 (19)* 129 (12)* 128 (14)* 128 (15)* 125 (13) * 124 (5)* 122 (4)*
DBP (mmHg) 78 (11) 73 (9)* 73 (8)* 71 (7)* 70 (10)* 69 (7)* 70 (6)* 69 (5)*
  Control group (n = 9)
Month of Study 0 6 12 24 48 72 96 120
FBG(mg/dl) 137 (17) 129 (14)* 126 (17)* 119 (13)* 112 (15)* 121 (11)* 124 (9)* 124 (9)*
HbA1c (%) 6.8 (0.25) 6.3 (0.43)* 6.3 (0.35)* 6.3 (0.33)* 6.2 (0.44)* 6.2 (0.55) * 6.4 (0.27)* 6.4 (0.26)*
BMI 22.1 (3.3) 22.6 (3.3) 22.5 (3.1) 22.5 (3.7) 22.7 (3.9) 22.7 (3.2) 22.4 (2.9) 22.5 (3.0)
hsCRP(ng/ml) 204 (97) 241 (63) 291 (96) 287 (78) 269 (102) 266 (75) 220 (163) 240 (174)
ACR(mg/gCr) 99 (233) 103 (267) 125 (284) 129 (305) 132 (299) 132 (211) 115 (154) 119 (148)
SBP (mmHg) 130 (12) 130 (15) 131 (13) 131 (11) 130 (14) 129 (15) 130 (14) 131 (15)
DBP (mmHg) 72 (8) 72 (9) 73 (12) 73 (9) 72 (8) 73 (12) 73 (7) 72 (10)
  1. Values are shown as means ± SD in parentheses
  2. FBG fasting bloodglucose, HbA1c hemoglobin A1c, BMI body mass index, hsCRP high sensitivity C-reactitive protein, ACR albumin-to-creatinine ratio, SBP systolic blood pressure, DBP diastolic blood pressure
  3. *Intragroup comparison: p < 0.05 (paired t test)