Table 4 Associations with CVD presented for three models
Cardiovascular disease | ||||||||
|---|---|---|---|---|---|---|---|---|
| Â | COR (CI 95%) | P value | Model 1a | Model 2b | Model 3c | |||
AOR (CI 95%) | P valuea | AOR (CI 95%) | P valueb | AOR (CI 95%) | P valuec | |||
Age (per year) | 1.16 (1.03–1.30) | 0.016 | 1.10 (0.98–1.25) | 0.12 | – | – | – | – |
Diabetes duration (per year) | 1.10 (1.014–1.15) | 0.016 | 1.10 (1.02–1.18) | 0.016 | 1.13 (1.03–1.24) | 0.008 | 1.10 (1.02–1.18) | 0.012 |
Abdominal obesity | 7.6 (1.6–35.5) | 0.009 | 10.2 (1.7–62) | 0.011 | 24.5 (2.8–217) | 0.004 | 15.8 (2.2–113) | 0.006 |
Depression | 7.8 (1.6–36.8) | 0.010 | 5.9 (0.9–40) | 0.069 | 22.1 (2.4–201) | 0.006 | 17.4 (2.2–135) | 0.006 |
Antihypertensive drugs (users) | 5.6 (1.1–29.2) | 0.043 | 1.7 (0.2–13.6) | 0.63 | – | – | – | – |
Statins (users) | 7.5 (0.9–63.2) | 0.06 | 3.0 (0.2–37) | 0.40 | – | – | – | – |
Antidepressants (users) | 12.3 (2.5–60.0) | 0.002 | 5.0 (0.8–32) | 0.090 | 4.8 (0.7–33) | 0.12 | 4.6 (0.6–35) | 0.13 |
MMP-14 (per ng/mL) | 1.01 (1.00–1.01) | 0.060 | – | – | 1.01 (1.00–1.02) | 0.005 | – | – |
High MMP-14 (≥  5.81 ng/mL) | 8.0 (1.5–42.4) | 0.014 | – | – | – | – | 14.2 (2.0–101) | 0.008 |
TIMP-2 (per ng/mL) | 1.01 (1.00–1.02) | 0.102 | – | – | – | – | – | – |
LDL-cholesterol (per mmol/L) | 0.3 (0.1–1.2) | 0.085 | 0.5 (0.1–2.4) | 0.38 | – | – | – | – |