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Table 3 Associations with high MMP-14

From: Galectin-3, metalloproteinase-2 and cardiovascular disease were independently associated with metalloproteinase-14 in patients with type 1 diabetes: a cross sectional study

 

High MMP-14 (≥  5.81 ng/mL)

COR (CI 95%)

P value

AOR (CI 95%)

P valuea

CVD

8.0 (1.5–42)

0.014

8.1 (1.3–52.5)

0.027

MMP-2 (per ng/mL)

1.01 (1.01–1.01)

0.016

1.01 (1.00–1.01)

0.044

TIMP-2 (per ng/mL)

1.00 (1.00–1.01)

0.13

1.00 (0.99–1.01)

0.92

Galectin-3 (per ng/mL)

2.15 (1.63–2.82)

<  0.001

2.19 (1.65–2.90)

<  0.001

HbA1c (mmol/mol)

0.98 (0.96–1.00)

0.054

0.98 (0.95–1.00)

0.10

  1. aMultiple logistic regression analysis: backward (Wald): N  =  263; Nagelkerke R Square: 0.320; Hosmer and Lemeshow Test: 0.630