Skip to main content

Table 1 Baseline variables presented for patients with and without cardiovascular disease

From: Galectin-3, metalloproteinase-2 and cardiovascular disease were independently associated with metalloproteinase-14 in patients with type 1 diabetes: a cross sectional study

 

All patients

High MMP-14 (≥  5.81 ng/mL)

Cardiovascular disease

Yes

No

Pa

Yes

No

Pa

N

268

67

201

 

7

261

 

Age (years)

(18–59)

42 (32, 48)

42 (31, 52)

0.60

55 (46, 59)

42 (31, 50)

0.003

Diabetes duration (years)

(1–55)

21 (9, 31)

20 (11, 30)

0.97

35 (19, 44)

20 (10, 30)

0.027

Sex

 Men

154 (58)

42 (63)

112 (56)

0.39b

4 (57)

150 (58)

1.00b

 Women

114 (42)

25 (37)

89 (44)

3 (43)

111 (42)

 

Abdominal obesityc

46 (16)

10 (15)

32 (16)

1.00b

4 (57)

38 (15)

0.014b

BMI (kg/m2)d

(18–45)

25 (23, 27)

25 (23, 28)

0.72

23 (22, 33)

25 (23, 27)

0.63

Systolic blood pressure (mm Hg)

(90–160)

125 (115, 130)

110 (120, 130)

0.21

120 (120, 135)

120 (110, 130)

0.38

Diastolic blood pressure (mm Hg)

(55–100)

70 (70, 78)

70 (68, 75)

0.40

75 (70, 75)

70 (70, 75)

0.64

Physical activitye

 Daily

93 (37)

27 (42)

66 (35)

0.99f

1 (14)

92 (37)

0.82f

 3–5/week

80 (31)

19 (29)

61 (32)

 

4 (57)

76 (31)

 1–2/week

54 (21)

13 (20)

41 (22)

 

2 (29)

52 (21)

 < 1/week

27 (11)

6 (9)

21 (11)

 

0

27 (11)

Smokingg

28 (11)

7 (11)

21 (11)

1.00

1 (14)

27 (11)

> 0.56b

CVD

7 (3)

5 (8)

2 (1)

0.012b

–

–

–

Depression

26 (10)

8 (12)

18 (9)

0.48b

3 (43)

23 (9)

0.022b

Thyroid diseaseh

28 (11)

4 (6)

24 (12)

0.25b

0

28 (11)

1.00b

CSIIi (users)

23 (9)

5 (8)

18 (9)

0.81b

0

23 (9)

1.00b

Antihypertensive drugs (users)

86 (32)

18 (27)

68 (34)

0.36b

5 (71)

81 (31)

0.037b

Statins (users)

122 (46)

30 (45)

92 (46)

1.00b

6 (86)

116 (44)

0.049b

Antidepressants (users)

18 (7)

6 (9)

12 (6)

0.37b

3 (43)

15 (6)

0.008b

  1. Data are presented as N (%), (min–max) or median (q1, q3)
  2. aMann–Whitney U test unless indicated
  3. bFisher’s Exact Test
  4. c5; d2; e14: missing values (N)
  5. fLinear-by-linear association
  6. g15; h9: missing values (N)
  7. iPatients not using CSII are using MDII