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Table 2 Multiple linear regression models displaying the effects of PSQI scores on the outcomes of glycemic variability parameters

From: Association of sleep quality with glycemic variability assessed by flash glucose monitoring in patients with type 2 diabetes

Models

B (95% CI)

β

t

p

Adjusted R2

SD

 Model 0: unadjusted

0.086 (0.038–0.134)

0.322

3.551

0.001

0.104

 Model 1: age, sex, BMI, WC, SBP, DBP and diabetes duration

0.080 (0.031–0.129)

0.300

3.231

0.002

0.145

 Model 2: Model 1  +  hypertension and glucose-lowering therapies

0.060 (0.014–0.106)

0.225

2.588

0.011

0.366

 Model 3: Model 2  +  eGFR, UA, lipid profiles, HbA1c, AUCglu, AUCcp and AUCgluca

0.065 (0.003–0.128)

0.251

2.112

0.041

0.678

CV

 Model 0: unadjusted

0.838 (0.427–1.250)

0.361

4.037

< 0.001

0.130

 Model 1: age, sex, BMI, WC, SBP, DBP and diabetes duration

0.810 (0.391–1.229)

0.348

3.832

< 0.001

0.179

 Model 2: Model 1  +  hypertension and glucose-lowering therapies

0.676 (0.254–1.099)

0.291

3.177

0.002

0.295

 Model 3: Model 2  +  eGFR, UA, lipid profiles, HbA1c, AUCglu, AUCcp and AUCgluca

0.667 (0.055–1.279)

0.286

2.207

0.033

0.618

MODD

 Model 0: unadjusted

0.072 (0.030–0.115)

0.308

3.381

0.001

0.095

 Model 1: age, sex, BMI, WC, SBP, DBP and diabetes duration

0.065 (0.022–0.109)

0.279

2.999

0.003

0.143

 Model 2: Model 1  +  hypertension and glucose-lowering therapies

0.050 (0.009–0.091)

0.213

2.402

0.018

0.342

 Model 3: Model 2  +  eGFR, UA, lipid profiles, HbA1c, AUCglu, AUCcp and AUCgluca

0.041 (–0.019 to 0.100)

0.188

1.374

0.177

0.575

MAGE

 Model 0: unadjusted

0.150 (0.075–0.225)

0.354

3.948

< 0.001

0.125

 Model 1: age, sex, BMI, WC, SBP, DBP and diabetes duration

0.138 (0.061–0.215)

0.326

3.563

0.001

0.169

 Model 2: Model 1  +  hypertension and glucose-lowering therapies

0.113 (0.038–0.187)

0.266

3.004

0.003

0.342

 Model 3: Model 2  +  eGFR, UA, lipid profiles, HbA1c, AUCglu, AUCcp and AUCgluca

0.135 (0.025–0.246)

0.323

2.489

0.018

0.614

TIR3.9–10

 Model 0: unadjusted

− 1.619 (− 2.353 to − 0.885)

− 0.386

− 4.373

< 0.001

0.149

 Model 1: age, sex, BMI, WC, SBP, DBP and diabetes duration

− 1.597 (− 2.345 to − 0.849)

− 0.381

− 4.236

< 0.001

0.196

 Model 2: Model 1  +  hypertension and glucose-lowering therapies

− 1.339 (− 2.076 to − 0.602)

− 0.319

− 3.607

< 0.001

0.347

 Model 3: Model 2  +  eGFR, UA, lipid Profiles, HbA1c, AUCglu, AUCcp and AUCgluca

− 1.701 (− 2.577 to − 0.825)

− 0.401

− 3.930

< 0.001

0.763

  1. PSQI Pittsburgh Sleep Quality Index; SD standard deviation of glucose; CV coefficient of variation of glucose; MAGE mean amplitude of glycemic excursions; MODD mean of daily differences; TIR3.9–10 time in glucose range of 3.9–10 mmol/L; BMI body mass index; WC waist circumference; SBP/DBP systolic/diastolic blood pressure; UA uric acid; HbA1c glycosylated hemoglobin A1c; eGFR estimated glomerular filtration rate; AUCglu area under the glucose curve; AUCgluca area under the glucagon curve; AUCcp area under the C-peptide curve