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Table 4 HbA1c and glycemic variations in type 1 and type 2 DM patient

From: Correlation between short- and mid-term hemoglobin A1c and glycemic control determined by continuous glucose monitoring

 

Total DM patient

 

After 1 month (n = 25)

After 2 month (n = 34)

After 3 month (n = 36)

Before 1 month (n = 55)

Before 2 month (n = 31)

Before 3 month (n = 36)

HbA1c

8.1 ± 1.4

8.4 ± 1.4

7.6 ± 1.2

8.5 ± 1.2

8.2 ± 1.2

8.2 ± 1.5

Mean glucose level (mg/dL)

158.1 ± 45.8

156.6 ± 36.8

155.7 ± 28.2

158.0 ± 30.5

170.5 ± 43.3

151.6 ± 30.4

SD (mg/dL)

39.1 ± 11.1

43.9 ± 17.7

45.1 ± 15.7

43.1 ± 13.4

45.8 ± 19.4

43.9 ± 13.6

MAGE (mg/dL)

108.1 ± 23.7

119.0 ± 35.5

117.0 ± 26.6

118.8 ± 33.8

120.0 ± 34.3

113.2 ± 30.0

CONGA-1 (mg/dL)

27.0 ± 7.5

30.6 ± 10.1

30.0 ± 7.8

29.8 ± 8.5

29.8 ± 8.7

29.9 ± 8.2

%CV

25.5 ± 7.4

28.4 ± 10.6

29.2 ± 9.5

27.6 ± 8.5

27.4 ± 10.9

29.3 ± 8.8

 

Type 1 DM patient

 

After 1 month (n = 7)

After 2 month (n = 9)

After 3 month (n = 11)

Before 1 month (n = 13)

Before 2 month (n = 10)

Before 3 month (n = 10)

HbA1c

7.7 ± 1.0

8.6 ± 1.2

8.1 ± 1.2

8.5 ± 1.1

8.0 ± 1.5

9.0 ± 1.8

Mean glucose level (mg/dL)

141.7 ± 19.0

147.7 ± 26.1

158.8 ± 24.8

158.2 ± 23.5

154.0 ± 31.0

150.0 ± 27.3

SD (mg/dL)

41.9 ± 10.0

56.4 ± 17.9

56.6 ± 16.4

55.0 ± 11.2

57.5 ± 25.4

49.5 ± 12.7

MAGE (mg/dL)

111.4 ± 17.4

138.6 ± 30.6

127.6 ± 16.9

140.2 ± 26.3

136.4 ± 39.5

122.2 ± 23.1

CONGA-1 (mg/dL)

31.8 ± 6.2

37.8 ± 7.6

34.9 ± 6.5

37.5 ± 7.2

35.7 ± 9.7

33.3 ± 8.0

%CV

29.5 ± 5.1

38.3 ± 9.5

34.0 ± 10.9

33.6 ± 9.6

36.6 ± 11.5

31.4 ± 10.5

 

Type 2 DM patient

 

After 1 month (n = 18)

After 2 month (n = 25)

After 3 month (n = 25)

Before 1 month (n = 42)

Before 2 month (n = 21)

Before 3 month (n = 26)

HbA1c

8.3 ± 1.5

8.4 ± 1.5

7.4 ± 1.2

8.4 ± 1.2

8.2 ± 1.0

7.9 ± 1.2

Mean glucose level (mg/dL)

164.5 ± 51.8

159.4 ± 40.0

153.0 ± 31.9

158.7 ± 33.1

173.8 ± 49.3

156.5 ± 32.5

SD (mg/dL)

37.7 ± 11.9

39.6 ± 15.9

40.7 ± 13.7

39.7 ± 12.6

39.8 ± 49.3

42.9 ± 14.3

MAGE (mg/dL)

109.1 ± 25.2

114.6 ± 33.9

109.6 ± 28.7

112.7 ± 33.9

115.2 ± 27.7

109.1 ± 33.7

CONGA–1 (mg/dL)

25.4 ± 7.2

28.0 ± 9.56

28.3 ± 8.5

28.0 ± 8.2

27.2 ± 6.6

29.2 ± 9.0

%CV

24.0 ± 7.7

24.8 ± 8.5

27.2 ± 8.2

25.7 ± 7.3

23.1 ± 7.4

28.5 ± 8.1

  1. HbA1c: hemoglobin A1c; SD: standard deviation; %CV: percentage coefficient of variation; MAGE: mean amplitude of glucose excursion; CONGA: Continuous overlapping net glycemic action (1 h intervals)