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Table 2 Incidence rate and adjusted odd ratios (95% confidence intervals) for the risk of insulin-requiring gestational diabetes by fatty liver index and each component of fatty liver index

From: Nonalcoholic fatty liver disease and the risk of insulin-requiring gestational diabetes

 

Events (n)

Incidence rate*

Model 1

Model 2

Model 3

Fatty liver index

 < 30

1570

5.3

1 (Ref.)

1 (Ref.)

1 (Ref.)

 30–59

267

36.8

5.70 (4.98,6.53)

3.53 (3.06,4.07)

3.50 (2.99,4.10)

 ≥ 60

147

62.4

9.96 (8.35,11.90)

4.83 (3.99,5.84)

4.19 (3.37,5.23)

Body mass index ≥ 25 kg/m2

 No

1413

4.9

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Yes

571

25.9

4.52 (4.09,5.00)

3.14 (2.83,3.49)

3.01 (2.67,3.39)

Waist circumference ≥ 85 cm

 No

1676

5.6

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Yes

308

29.6

4.45 (3.92,5.04)

2.89 (2.54,3.29)

2.85 (2.46,3.30)

Triglyceride ≥ 150 mg/dl or lipid lowering treatment

 No

1584

5.4

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Yes

400

27.6

4.30 (3.84,4.81)

2.82 (2.50,3.18)

2.79 (2.44,3.20)

Gamma-glutamyl transferase (GGT) highest quartile, ≥ 18 IU/L

 No

1007

4.3

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Yes

977

12.9

2.78 (2.54,3.04)

2.19 (2.00,2.40)

2.22 (2.00,2.47)

  1. *Per 1000 person-years
  2. Model 1: Adjusted for age
  3. Model 2: Adjusted for age, smoking, alcohol drinking, regular exercise, income status, fasting blood glucose, and dyslipidemia
  4. Model 3: Adjusted for model 2 + family history of diabetes