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Table 1 Characteristics of the study participants

From: Human Leukocyte Antigens class II (HLA II) gene profile from an admixed population of patients with type 1 diabetes with severe diabetic retinopathy: a nested case-control study in Brazil

Variable

Patients with severe DR, N  =  117

Patients without DR, N  =  117

p value

Sociodemographic

 Gender, N (%)

  

0.011

  Male

57 (48.72)

38 (32.48)

 

  Female

60 (51.28)

79 (67.52)

 

 Age, y mean (SD)

38.8 (11.68)

34.56 (12.32)

0.007

 Economic status, N (%)

  

0.237

  High

4 (3.42)

7 (5.98)

 

  Medium

52 (44.44)

49 (41.88)

 

  Low

52 (44.44)

58 (49.57)

 

  Very low

9 (7.69)

3 (2.56)

 

 Years of schooling, y mean (SD)

11.98 (3.99)

12.50 (3.68)

0.300

Diabetes-related variables

 HbA1c (%), mean (SD)

8.89 (1.87)

8.40 (1.74)

0.043

 HbA1c mmol/mol, mean (SD)

73.64 (20.41)

68.38 (19.01)

0.043

 Duration of diabetes, y mean (SD)

23.42 (9.28)

22.18 (8.32)

0.283

 GFR

66.62 (24.35)

83.04 (25.60)

< 0.001

 Arterial hypertension, y, N (%)

50 (42.68)

21 (17.95)

< 0.001

Self-reported ethnicity, N (%)

  

0.320

 Caucasian

62 (52.99)

65 (55.55)

 Black

15 (12.82)

9 (7.69)

 Mullatos

36 (30.77)

41 (35.04)

 Native Americans

4 (3.42)

1 (0.85)

 Asian

0

1 (0.85)

  1. Bold represents statistical significance (p < 0.05)
  2. Data are present as number (percentage), mean  ±  SD (standard deviation), or median (IQR or range)
  3. DR diabetic retinopathy; y years