Table 1 Baseline characteristics of non-obese and overweight patients with type 1 diabetes
From: Overweight and obesity in type 1 diabetes is not associated with higher ghrelin concentrations
BMI < 25a | BMI ≥ 25a | P < 0.05 | |
|---|---|---|---|
Patients (men) | 9 (6) | 9 (4) | NS |
Mean BMI (kg/m2) | 22.7 ± 1.8 | 30.12 ± 3,4 | NS |
Age (years) | 41 ± 9 | 54 ± 15 | NS |
Age at diagnosis | 24 ± 13 | 24 ± 14 | NS |
Duration of diabetes (years) | 23 ± 18 | 28 ± 17 | NS |
Alcohol users (n) | 9 | 7 | NS |
Smoking (n) | 4 | 4 | NS |
Number of statin users | 4 | 7 | NS |
Mean systolic RR (mmHg) | 131 ± 16 | 149 ± 17 | NS |
Mean diastolic RR (mmHg) | 75 ± 13 | 73 ± 11 | NS |
Creatinine (μmol/L) | 75 ± 8 | 89 ± 21 | NS |
Triglyceride (mmol/L) | 1.03 ± 0.51 | 1.38 ± 0.69 | NS |
Total cholesterol (mmol/L) | 4.6 ± 0.7 | 4,6 ± 1.3 | NS |
Mean LDL-cholesterol (mmol/L) | 2.6 ± 0.9 | 2.7 ± 1.0 | NS |
apo B (g/L) | 0.8 ± 0.2 | 1.0 ± 0.4 | NS |
mean HbA1C (mmol/mol) | 53.5 ± 6.5 | 60.3 ± 7.2 | NS |
Albumin/creatinine ratio (g/mol) | 0.01 ± 0.00 | 0.02 ± 0.02 | NS |
Mean acylated ghrelin (pg/ml) | 44.5 ± 29.4 | 46.1 ± 29.6 | NS |
Mean unacylated ghrelin (pg/ml) | 42.4 ± 20.7 | 47.2 ± 18.2 | NS |
ratio AG/UAG | 1.1 ± 0.6 | 1.0 ± 0.5 | NS |
mean insulin dose (range 20 to 100) units per day | 36.6 ± 17.0 | 52.6 ± 27.2 | P < 0.02 |
Positive anti-GAD65 | 4 | 6 | NS |