|
Gender
|
|
Female
|
26 (36.1%)
|
44 (62.9%)
|
0.8
|
|
Male
|
46 (39.9%)
|
72 (61.0%)
| |
|
Age
|
68.62 ± 17.27
|
62.09 ± 15.13
|
0.006
|
|
Age class (years)
|
|
29–59
|
21 (29.2%)
|
51 (44%)
| |
|
≥ 60
|
51 (70.8%)
|
65 (56%)
|
0.042
|
|
Clinical outcome
|
|
Mortality
|
13 (18.1%)
|
6 (5.2%)
|
0.004
|
|
Mortality by gender
|
|
Female
|
6 (23.1%)
|
2 (4.5%)
| |
|
Male
|
7 (15.2%)
|
4 (5.6%)
|
1
|
|
Comorbidities
|
|
Obesity
|
15 (20.8%)
|
16 (13.8%)
|
0.206
|
|
Cardiopathy
|
24 (33.3%)
|
17 (25.3%)
|
0.003
|
|
Hypertension
|
55 (76.4%)
|
70 (60.3%)
|
0.023
|
|
COPD/pneumonia
|
11 (15.3%)
|
6 (5.17%)
|
0.019
|
|
Smoking/former smoking
|
6 (8.3%)
|
9 (7.8%)
|
0.888
|
|
Neurological disease
|
9 (12.5%)
|
4 (3.4%)
|
0.017
|
|
CKD
|
8 (11.1%)
|
3 (2.6%)
|
0.015
|
|
Thyroid
|
10 (13.9%)
|
14 (12.1%)
|
0.716
|
|
Dyslipidemia
|
31 (43.1%)
|
39 (33.6%)
|
0.193
|
|
Neoplasia/immuno
|
3 (4.2%)
|
9 (7.8%)
|
0.327
|
|
Asthma
|
2 (2.8%)
|
2 (1.7%)
|
0.638
|
|
BMI
|
29.49 ± 4.96
|
29.203 ± 5.38
|
0.714
|
|
In-hospital Clinical characteristics
|
|
NEWS
|
4.25 ± 3.43
|
2.45 ± 2.51
|
0.001
|
|
Time of stay in ICU
|
4 (0–58)
|
1 (0–94)
|
0.157
|
|
Time of stay in nursery
|
6 (0–58)
|
7 (9–28)
|
0.285
|
|
Total hospitalization time
|
11 (2–72)
|
10 (2–100)
|
0.119
|
|
Time of MV
|
0 (0–50)
|
0 (0–63)
|
0.168
|
|
In-hospital metformin therapy
|
18 (25%)
|
97 (83.6%)
|
0.000
|
|
In-hospital max dose of metformin
|
1158.33 ± 403.75
|
1265.98 ± 605.77
|
0.349
|
|
In-hospital time of metformin therapy
|
6 (1–22)
|
6 (1–56)
|
0.554
|
|
Pre-hospital metformin therapy
|
0
|
116
|
–
|
|
Pre-hospital metformin daily dose
|
–
|
1144.71 ± 622.55
|
–
|
|
In-hospital insulin therapy
|
25 (34.7%)
|
36 (31.0%)
|
0.600
|
|
In-hospital time of insulin therapy
|
7 (1–55)
|
5 (1–98)
|
0.844
|
|
Orotracheal intubation
|
22 (30.6%)
|
23 (20.5%)
|
0.123
|
|
Prisma
|
10 (13.9%)
|
5 (4.5%)
|
0.023
|
|
Prone
|
4 (5.6%)
|
3 (2.7%)
|
0.312
|
|
Vasoactive drugs
|
21 (29.2%)
|
16 (14.3%)
|
0.014
|
|
CLHO/HCQ
|
10 (13.9%)
|
5 (4.5%)
|
0.023
|
|
Dexamethasone/prednisolone
|
67 (93.1%)
|
102 (87.9%)
|
0.257
|
