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Table 1 Demographic and clinical characteristics of all patients hospitalized with Covid-19 and univariate in-hospital risk factors associated with in-hospital mortality and orotracheal intubation

From: Outcome and death risk of diabetes patients with Covid-19 receiving pre-hospital and in-hospital metformin therapies

Clinical features All patients (n = 1170) number (%) median (max–min) Mortality risk factors OR (CI 95%) Orotracheal intubation risk factor OR (CI 95%)
Gender
 Man 618 (52.8%) 1.078 (0.608–1.91) 0.669 (0.43–1.03)
 Woman 552 (47.2%)   
Age, years 51.8 ± 18.4 1.14 (1.11–1.17) 1.05 (1.04–1.07)
Age class
  < 29 87 (7.4%)   
 29–59 713 (60.9%)   
  ≥ 60 370 (31.6%) 119.11 (16.37–54.3)* 9.24 (2.22–38.51)*
Clinical outcome
 Mortality 49 (4.2%)
Mortality by age class
  < 29 0 (0%)
 29–59 1 (0.1%)
  ≥ 60 48 (13%)
Comorbidities
 Diabetes (type I or II) 188 (16.1%) 3.57 (1.96–6.48) 6.08 (3.9–9.47)
 Obesity 122 (10.4%) 0.97 (0.38–2.51) 2.03 (1.15–3.56)
 Cardiopathy 112 (9.66%) 6.34 (3.42–11.77) 3.14 (1.84–5.34)
 Hypertension 368 (31.5%) 5.92 (3.14–11.14) 4.00 (2.59–6.2)
 COPD/pneumonia 62 (5.3%) 6.95 (3.41–14.33) 2.68 (1.34–5.34)
 Smoking/former smoking 43 (3.6%) 2.46 (0.85–7.2) 1.16 (0.41–3.33)
 Neurological disease 70 (6.05%) 7.6 (2.072–24.93) 3.14 (1.67–5.88)
CKD 28 (2.4%) 8.73 (3.52–21.67) 8.13 (3.69–17.93)
 Thyroid disease 111 (9.5%) 1,63 (0.71–3.72) 2.23 (1.06–4.71)
 Dyslipidemia 171 (14.6%) 3.02 (1.64–5.62) 1.59 (0.85–2.97)
 Neoplasia/immuno 57 (4.9%) 2.34 (0.89–6.14) 2.83 (1.76–4.57)
 Asthma 51 (4.4%) 0.45 (0.06–3.3) 3.18 (0.43–23.3)
In-hospital clinical characteristics
 NEWS/PEWS 1 (0–13.2) 1.5 (1.36–1.63) 1.38 (1.28–1.48)
 Time of stay in ICU 0 (0–107) 1.082 (1.058–1.11) 1.42 (1.34–1.5)
 Time of stay in nursery 5.0 (0–61) 0.95 (0.88–1.02) 1.09 (1.06–1.12)
 Time of hospitalization 6.0 (1–112) 1.047 (1.03–1.06) 1.18 (1.15–1.21)
 Time of MV 0 (0–66) 1.16 (1.12–1.21) NS
 Orotracheal intubation 94 (8%) 35.2 (18.42–67.65)
 Prisma 24 (2.4%) 44.162 (19.36–100.74) NS
 Prona 18 (1.5%) 6.93 (2.19–21.88) 233.8 (30.7–1280.23)
 Vasoactive drugs 72 (6.2%) 32.15 (16.93–61.044) 690.46 (234.27–2034.92)
 CLHO/HCQ 76 (6.5%) 1.11 (1.03–1.21) 22.83 (5.2–100.17)
  1. NS, not significant, Neoplasia/immune, neoplasia/immunosuppression; Time of MV, Time of mechanical ventilation; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; NEWS/PEWS, National Early Warning Score/Pediatric Early Warning Score; Prisma, prisma hemodialysis machine; Prona, prone position; CLHO/HCQ, Chloroquine/hydroxychloroquine; *compared with 29–59 group. Bold: p < 0.05