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Fig. 8 | Diabetology & Metabolic Syndrome

Fig. 8

From: Circ-ACTR2 aggravates the high glucose-induced cell dysfunction of human renal mesangial cells through mediating the miR-205-5p/HMGA2 axis in diabetic nephropathy

Fig. 8

Circ-ACTR2 regulated the HMGA2 level by acting as a sponge of miR-205-5p. A, B The mRNA (A) and protein (B) levels of HMGA2 were respectively detected by qRT-PCR and western blot after transfection of si-NC, si-circ-ACTR2, si-circ-ACTR2 + anti-miR-NC or si-circ-ACTR2 + anti-miR-205-5p in HG-treated HRMCs. **P < 0.01, ****P < 0.0001

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