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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Circ-ACTR2 aggravates the high glucose-induced cell dysfunction of human renal mesangial cells through mediating the miR-205-5p/HMGA2 axis in diabetic nephropathy

Fig. 2

HG-induced cell damages in HRMCs were partly reversed by the silence of circ-ACTR2. A The expression of circ-ACTR2 was quantified using qRT-PCR in four groups of control, HG, HG + si-NC, HG + si-ACTR2 in HRMCs. B Cell viability detection was performed by CCK-8 assay. C Inflammatory cytokines IL-6 and TNF-α were determined by ELISA. D Cell proliferation analysis was performed by EdU assay. E The protein examination of collagen I and collagen IV was conducted by western blot. F, G SOD activity (F) and MDA level (G) were respectively measured using the corresponding kits. **P < 0.01, ***P < 0.001, ****P < 0.0001

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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