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Table 3 Pulse wave velocity and white matter hyperintensity progression

From: Arterial stiffness and progression of cerebral white matter hyperintensities in patients with type 2 diabetes and matched controls: a 5-year cohort study

Linear regression
  All (n  =  104) p DM (n  =  45) p Controls (n  =  59) p
% change in cWMH volume per 1 m/s increase in PWV (95% CI)s
 Crude 34 (20–51) < 0.01 32 (12–56) < 0.01 48 (8–102) < 0.05
 Adjusteda 16 (1–32) < 0.05 18 (− 5 to 47) 0.13 31 (− 8 to 87) 0.13
% change cWMH volume if PWV  >  8.94 m/s
 Crude 208 (73–451) < 0.01 214 (57–526) < 0.01 218 (18–756) < 0.05
 Adjusteda 92 (2–263) < 0.05 88 (− 20 to 339) 0.14 161 (− 5 to 618) 0.06
  1. cWMH white matter hyperintensities corrected for intracranial volume; PWV pulse wave velocity
  2. aAdjusted model: age, sex, diabetes status (yes/no), baseline pulse pressure and smoking status (no smoking or current/former smoking). In separate group analysis, diabetes status was omitted