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Table 1 Characterisitics of clinical variables in HC and patients with T2D

From: Serum fatty acid-binding protein 4 levels and responses of pancreatic islet β-cells and α-cells in patients with type 2 diabetes

Variables

HC

T2D

t/Z /χ2 value

p value

n

89

115

 − 

 − 

Female, n (%)

47 (52.8)

42 (36.5)

5.412

0.020

Age (years)

55.06 ± 8.82

55.32 ± 11.42

0.128

0.856

BMI (kg/m2)

23.00 ± 2.42

24.92 ± 3.81

4.375

0.001

WC (cm)

 − 

90.80 ± 9.41

 − 

 − 

SBP (mmHg)

121.53 ± 10.98

132.84 ± 16.39

5.890

 < 0.001

DBP (mmHg)

78.17 ± 7.53

79.21 ± 10.70

0.823

0.412

Diabetic duration (year)

 − 

8 (2−10)

 − 

 − 

Glucose-lowering therapies

    

 Lifestyle alone, n (%)

 − 

32 (27.8)

 − 

 − 

 Insulin treatments, n(%)

 − 

35 (30.4)

 − 

 − 

 Insulin secretagogues, n (%)

 − 

39 (33.9)

 − 

 − 

 Metformin, n (%)

 − 

53 (46.1)

 − 

 − 

 Pioglitazone, n (%)

 − 

10 (8.7)

 − 

 − 

 AGIs, n (%)

 − 

13 (11.3)

 − 

 − 

 GLP-1RAs, n (%)

 − 

1 (0.9)

 − 

 − 

 DPP-4Is, n (%)

 − 

8 (7.0)

 − 

 − 

FPG (mmol/L)

5.18 ± 0.48

11.07 ± 3.58

17.426

 < 0.001

TG (mmol/L)

1.33(1.01 − 1.86)

1.47 (0.96−2.84)

1.415

0.157

TC (mmol/L)

4.72 ± 0.72

4.73 ± 1.48

0.053

0.958

HDLC (mmol/L)

1.45 ± 0.32

1.17 ± 0.31

 − 6.107

 < 0.001

LDLC (mmol/L)

3.00 ± 0.62

2.91 ± 1.04

− 0.737

0.462

eGFR (ml/min/1.73 m2)

128.36(92.48−151.86)

121.81 (90.93−146.78)

− 3.427

0.078

Serum UA (umol/L)

295.90 ± 75.06

317.00 ± 115.21

1.532

0.127

HbA1c (%)

 − 

9.60 ± 2.07

 − 

 − 

FABP4 (pg/ml)

9498.46

(5168.19−14406.19)

17535.96

(9513.62−28436.53)

6.107

 < 0.001

  1. Student t-tests, Mann–Whitney U tests and Chi-square tests were applied to detect differences in their corresponding type of data, and corresponding test statistics (t, Z and χ2 values) and p values were also provided