Table 1 Patient characteristics and disposition

Age (years), mean (SD)

52.0 (10.0)

53.4 (9.7)

52.7 (9.9)

54.3 (9.4)

Age group, n (%)

 < 40

31 (11.7)

24 (8.9)

55 (10.2)

159 (8.0)

 40 −  < 65

214 (80.5)

220 (81.2)

434 (80.8)

223 (11.1)

  ≥ 65

21 (7.9)

27 (10.0)

48 (8.9)

1619 (80.9)

 Women, n (%)

153 (57.5)

163 (60.1)

316 (58.8)

1060 (53.0)

Predominant race, n (%)

 Native American

102 (38.3)

107 (39.5)

209 (38.9)

210 (10.5)

 Caucasian

96 (36.1)

91 (33.6)

187 (34.8)

1217 (60.8)

 Median (IQR) duration of T2DM (months)

4.2 (1.6, 11.1)

4.4 (1.1, 11.9)

4.3 (1.3, 11.5)

3.3 (0.9, 10.0)

HbA1c (%)^a

 Mean (SD)

6.7 (0.5)

6.7 (0.5)

6.7 (0.5)

6.7 (0.5)

 ˂7.0%, n (%)

191 (71.8)

196 (72.3)

387 (72.1)

1427 (71.3)

  ≥ 7.0%, n (%)

75 (28.2)

75 (27.7)

150 (27.9)

572 (28.6)

 Median (IQR) FPG (mmol/L)^a

6.6 (5.8, 7.4)

6.6 (5.8, 7.5)

6.6 (5.8, 7.5)

6.9 (6.1, 7.8)

BMI (kg/m²)

 Mean (SD)

31.0 (4.6)

31.0 (4.7)

31.0 (4.7)

31.1 (4.7)

 < 30 kg/m², n (%)

122 (45.9)

123 (45.4)

245 (45.6)

875 (43.7)

 ≥ 30 kg/m², n (%)

144 (54.1)

148 (54.6)

292 (54.4)

1126 (56.3)

GFR (mL/min/1.73 m²)^b

 Normal (˃80)

202 (75.9)

217 (80.1)

419 (78.0)

1321 (66.1)

 Mild (≥ 50– ≤ 80)

64 (24.1)

54 (19.9)

118 (22.0)

670 (33.5)

 Median (IQR) weight (kg)

77.8 (69.0, 92.5)

78.4 (68.0, 90.0)

78.0 (68.5, 91.5)

84.3 (72.3, 97.0)

Current smokers, n (%)

32 (12.0)

29 (10.7)

61 (11.4)

290 (14.5)

Discontinued study participation prematurely, n (%)

51 (19.2)

58 (21.4)

109 (20.3)

403 (20.1)