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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Circ-PNPT1 contributes to gestational diabetes mellitus (GDM) by regulating the function of trophoblast cells through miR-889-3p/PAK1 axis

Fig. 2

Circ-PNPT1 is highly expressed in placental tissues of GDM and HG-stimulated trophoblast cells. A qRT-PCR analysis of circ-PNPT1 expression in placental tissues with GDM or not. B qRT-PCR analysis of circ-PNPT1 expression in HTR8/SVneo cells treated with HG or normal glucose (control) for 48 h. C qRT-PCR analysis of circ-PNPT1 and linear PNPT1 mRNA expression in HTR8/SVneo cells after RNase R treatment. D qRT-PCR analysis of the levels of circ-PNPT1, GAPDH, and U6 in purified HTR8/SVneo nuclear and cytoplasmic fractions. ***P < 0.001, ****P < 0.0001

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