Fig. 1

HG suppresses trophoblast cell viability, migration, invasion, and induces apoptosis in vitro. A–E HTR8/SVneo cells were treated with HG or normal glucose (control) for 48 h. A CCK-8 assay for cell viability. B Flow cytometric analysis of cell apoptosis. C, D Transwell assay of cell migration and invasion. E Wound healing assay for cell migration. **P < 0.01, ***P < 0.001