Skip to main content

Table 4 Results of two different binary logistic regression analyses with prediabetes (versus healthy controls) and Prediabetes-IR versus Prediabetes+IR as dependent variables and the biomarkers as explanatory variables

From: The immune-opioid axis in prediabetes: predicting prediabetes with insulin resistance by plasma interleukin-10 and endomorphin-2 to kappa-opioid receptors ratio

Dichotomies

Explanatory variables

B

SE

Wald

df

p

OR

95% CI

Prediabetes/Controls

IL-10

0.359

0.128

7.876

1

0.005

1.431

1.114–1.839

zLnβEP

0.316

0.137

5.311

1

0.021

1.372

1.048–1.795

zLnEM2

0.846

0.396

4.569

1

0.033

2.331

1.073–5.063

Prediabetes-IR/Prediabetes+IR

IL-10

0.618

0.05

2.505

1

0.043

1.083

0.981–1.195

zLnEM2/KOR

0.555

0.433

4.846

1

0.024

2.611

1.187–3.947

  1. zLn: z-score of the natural logarithm; IL: interleukin; KOR: κ-opioid receptor; MOR: µ-opioid receptor; EM2: Endomorphin-2; βEP: β-endorphin; IR: insulin resistance (HOMA2IR > 2.5)