Tertiles of ELIH | P_trend | Tertiles of EDIH | P_trend | |||||
---|---|---|---|---|---|---|---|---|
T1 | T2 | T3 | T1 | T2 | T3 | |||
Hyperinsulinemia | ||||||||
Median score | 1.04 | 1.28 | 1.55 | 0.02 | 0.14 | 0.37 | ||
Case/Total | 34/273 | 59/264 | 68/258 | 64/261 | 41/268 | 57/272 | ||
Model 1a | 1.00 (Ref.) | 2.14 (1.33–3.45) | 2.66 (1.66–4.28) | < 0.001 | 1.00 (Ref.) | 0.55 (0.35–0.88) | 0.72 (0.47–1.12) | 0.331 |
Model 2b | 1.00 (Ref.) | 2.15 (1.33–3.46) | 2.62 (1.62–4.22) | < 0.001 | 1.00 (Ref.) | 0.56 (0.35–0.89) | 0.73 (0.45–1.17) | 0.376 |
Model 3c | 1.00 (Ref.) | 2.15 (1.33–3.46) | 2.61 (1.62–4.22) | < 0.001 | 1.00 (Ref.) | 0.56 (0.35–0.89) | 0.73 (0.45–1.16) | 0.542 |
Insulin resistance | ||||||||
Median score | 1.03 | 1.27 | 1.51 | 0.02 | 0.15 | 0.40 | ||
Case/Total | 40/236 | 74/234 | 89/230 | 66/232 | 64/237 | 73/236 | ||
Model 1a | 1.00 (Ref.) | 2.26 (1.45–3.52) | 2.95 (1.90–4.58) | < 0.001 | 1.00 (Ref.) | 1.03 (0.68–1.57) | 1.22 (0.80–1.84) | 0.314 |
Model 2b | 1.00 (Ref.) | 2.25 (1.44–3.51) | 2.87 (1.84–4.47) | < 0.001 | 1.00 (Ref.) | 0.97 (0.63–1.50) | 1.10 (0.70–1.74) | 0.597 |
Model 3c | 1.00 (Ref.) | 2.24 (1.43–3.50) | 2.83 (1.82–4.26) | < 0.001 | 1.00 (Ref.) | 0.96 (0.62–1.48) | 1.10 (0.70–1.73) | 0.614 |
β-cell dysfunction | ||||||||
Median score | 1.09 | 1.35 | 1.66 | 0.02 | 0.15 | 0.39 | ||
Case/Total | 107/314 | 68/314 | 43/304 | 89/309 | 64/314 | 68/317 | ||
Model 1a | 1.00 (Ref.) | 0.51 (0.35–0.73) | 0.29 (0.19–0.44) | < 0.001 | 1.00 (Ref.) | 0.60 (0.41–0.88) | 0.76 (0.52–1.11) | 0.566 |
Model 2b | 1.00 (Ref.) | 0.51 (0.35–0.74) | 0.30 (0.19–0.45) | < 0.001 | 1.00 (Ref.) | 0.64 (0.43–0.96) | 0.84 (0.55–1.27) | 0.592 |
Model 3c | 1.00 (Ref.) | 0.52 (0.36–0.76) | 0.30 (0.19–0.45) | < 0.001 | 1.00 (Ref.) | 0.66 (0.44–0.98) | 0.84 (0.55–1.27) | 0.581 |
Insulin insensitivity | ||||||||
Median score | 1.03 | 1.27 | 1.51 | 0.02 | 0.15 | 0.40 | ||
Case/Total | 40/234 | 73/233 | 89/231 | 66/231 | 64/237 | 72/235 | ||
Model 1a | 1.00 (Ref.) | 2.23 (1.43–3.48) | 2.89 (1.86–4.50) | < 0.001 | 1.00 (Ref.) | 1.01 (0.67–1.54) | 1.17 (0.77–1.78) | 0.403 |
Model 2b | 1.00 (Ref.) | 2.23 (1.43–3.49) | 2.82 (1.81–4.39) | < 0.001 | 1.00 (Ref.) | 0.95 (0.61–1.46) | 1.04 (0.66–1.63) | 0.793 |
Model 3c | 1.00 (Ref.) | 2.31 (1.42–3.48) | 2.78 (1.78–4.34) | < 0.001 | 1.00 (Ref.) | 0.93 (0.60–1.44) | 1.03 (0.65–1.62) | 0.812 |