Tertiles of ELIH | P_trend | Tertiles of EDIH | P_trend | |||||
---|---|---|---|---|---|---|---|---|
T1 | T2 | T3 | T1 | T2 | T3 | |||
Hyperinsulinemia | ||||||||
Median score | 1.04 | 1.28 | 1.55 | 0.01 | 0.14 | 0.37 | ||
Case/Total | 36/283 | 63/283 | 71/282 | 68/285 | 45/285 | 58/285 | ||
Model 1a | 1.00 (Ref.) | 2.05 (1.29–3.26) | 2.46 (1.55–3.90) | < 0.001 | 1.00 (Ref.) | 0.60 (0.38–0.93) | 0.74 (0.48–1.14) | 0.609 |
Model 2b | 1.00 (Ref.) | 2.06 (1.30–3.28) | 2.41 (1.51–3.85) | < 0.001 | 1.00 (Ref.) | 0.61 (0.38–0.95) | 0.75 (0.47–1.19) | 0.633 |
Model 3c | 1.00 (Ref.) | 2.07 (1.30–3.29) | 2.42 (1.52–3.86) | < 0.001 | 1.00 (Ref.) | 0.60 (0.38–0.95) | 0.75 (0.47–1.19) | 0.618 |
Insulin resistance | ||||||||
Median score | 1.03 | 1.27 | 1.51 | 0.02 | 0.15 | 0.40 | ||
Case/Total | 43/242 | 81/242 | 93/241 | 74/244 | 67/243 | 76/243 | ||
Model 1a | 1.00 (Ref.) | 2.28 (1.48–3.51) | 2.80 (1.82–4.29) | < 0.001 | 1.00 (Ref.) | 0.98 (0.66–1.48) | 1.16 (0.78–1.74) | 0.434 |
Model 2b | 1.00 (Ref.) | 2.28 (1.48–3.51) | 2.74 (1.78–4.21) | < 0.001 | 1.00 (Ref.) | 0.94 (0.62–1.43) | 1.09 (0.70–1.69) | 0.495 |
Model 3c | 1.00 (Ref.) | 2.30 (1.49–3.55) | 2.71 (1.75–4.18) | < 0.001 | 1.00 (Ref.) | 0.94 (0.62–1.44) | 1.09 (0.70–1.70) | 0.475 |
β-cell dysfunction | ||||||||
Median score | 1.09 | 1.35 | 1.66 | 0.02 | 0.15 | 0.39 | ||
Case/Total | 110/319 | 72/320 | 53/320 | 100/323 | 67/322 | 71/322 | ||
Model 1a | 1.00 (Ref.) | 0.51 (0.35–0.74) | 0.31 (0.20–0.46) | < 0.001 | 1.00 (Ref.) | 0.57 (0.39–0.83) | 0.70 (0.48–1.01) | 0.229 |
Model 2b | 1.00 (Ref.) | 0.51 (0.35–0.75) | 0.32 (0.21–0.48) | < 0.001 | 1.00 (Ref.) | 0.60 (0.41–0.88) | 0.76 (0.51–1.15) | 0.430 |
Model 3c | 1.00 (Ref.) | 0.52 (0.36–0.76) | 0.30 (0.19–0.45) | < 0.001 | 1.00 (Ref.) | 0.60 (0.40–0.89) | 0.79 (0.52–1.20) | 0.437 |
Insulin insensitivity | ||||||||
Median score | 1.03 | 1.27 | 1.51 | 0.02 | 0.15 | 0.40 | ||
Case/Total | 43/240 | 80/241 | 93/242 | 74/243 | 67/243 | 75/242 | ||
Model 1a | 1.00 (Ref.) | 2.26 (1.47–3.47) | 2.75 (1.79–4.21) | < 0.001 | 1.00 (Ref.) | 0.96 (0.64–1.45) | 1.12 (0.75–1.68) | 0.497 |
Model 2b | 1.00 (Ref.) | 2.26 (1.47–3.49) | 2.69 (1.75–4.13) | < 0.001 | 1.00 (Ref.) | 0.92 (0.60–1.39) | 1.03 (0.66–1.59) | 0.803 |
Model 3c | 1.00 (Ref.) | 2.28 (1.48–3.53) | 2.65 (1.72–4.10) | < 0.001 | 1.00 (Ref.) | 0.92 (0.60–1.40) | 1.03 (0.66–1.61) | 0.796 |