Variables | Total | Q1 | Q2 | Q3 | Q4 | p value | ||
---|---|---|---|---|---|---|---|---|
ADA (U/L) | 13.6 (11.1–16.9) | 9.5 (8.5–10.3) | 12.4 (12.4–13.1) | 15.0 (14.3–16.0) | 19.7 (18.1–21.7) |  < 0.001 | ||
 n | 1573 | 396 | 399 | 388 | 390 | – | ||
Glu0 (mmol/L) | 11.39 ± 3.54 | 10.05 ± 3.32 | 11.29 ± 3.24 | 11.43 ± 3.39 | 12.83 ± 3.66 |  < 0.001 | ||
Glu30 (mmol/L) | 11.99 ± 2.75 | 11.71 ± 2.55 | 12.06 ± 2.68 | 12.05 ± 2.87 | 12.15 ± 2.88 | 0.024 | ||
Glu60 (mmol/L) | 15.33 ± 3.34 | 15.02 ± 3.26 | 15.27 ± 3.22 | 15.37 ± 3.38 | 15.66 ± 3.47 | 0.007 | ||
Glu120 (mmol/L) | 16.53 ± 4.11 | 15.30 ± 4.21 | 16.25 ± 3.90 | 16.90 ± 3.99 | 17.68 ± 3.98 |  < 0.001 | ||
Glu180 (mmol/L) | 12.67 ± 4.23 | 11.06 ± 4.00 | 12.28 ± 4.11 | 13.18 ± 4.13 | 14.19 ± 4.05 |  < 0.001 | ||
CP0 (ng/mL) | 1.17 (0.78–1.75) | 1.26 (0.83–1.75) | 1.15 (0.74–1.75) | 1.18 (0.74–1.82) | 1.11 (0.80–1/69) | 0.543 | ||
CP30 (ng/mL) | 2.02 (1.36–2.89) | 2.13 (1.49–3.12) | 2.01 (1.34–2.90) | 2.07 (1.33–2.87) | 1.90 (1.25–2.70) | 0.008 | ||
CP60 (ng/mL) | 3.02 (2.04–4.38) | 3.28 (2.35–4.64) | 3.06 (2.07–4.46) | 2.90 (2.05–4.38) | 2.79 (1.83–3.86) |  < 0.001 | ||
CP120 (ng/mL) | 4.20 (2.94–5.98) | 4.50 (3.16–6.26) | 4.19 (2.83–6.02) | 4.18 (2.93–5.99) | 3.83 (2.71–5.55) | 0.003 | ||
CP180 (ng/mL) | 5.28 (2.72–5.28) | 3.85 (2.74–5.36) | 3.69 (2.65–5.10) | 3.79 (2.79–5.39) | 3.73 (2.65–5.25) | 0.805 | ||
 ISHOMA-cp | 1.79 (1.20–2.52) | 1.95 (1.37–2.72) | 1.82 (1.24–2.58) | 1.86 (1.16–2.56) | 1.56 (1.06–2.33) |  < 0.001 | ||
 ISIM-cp | 456.62 (328.50–619.82) | 484.06 (355.65–646.62) | 467.68 (331.12–620.50) | 450.20 (320.57–622.24) | 425.43 (306.25–563.45) | 0.001 | ||
 AUCcp | 9.84 (6.93–13.70) | 10.64 (7.47–14.31) | 9.74 (6.84–13.96) | 9.88 (6.92–14.01) | 9.30 (6.42–12.73) | 0.005 | ||
 AUCglu | 41.96 ± 9.06 | 39.48 ± 8.92 | 41.47 ± 8.48 | 42.67 ± 9.02 | 44.28 ± 9.15 |  < 0.001 | ||
 AUCcp/glu | 0.23 (0.15–0.35) | 0.27 (0.18–0.39) | 0.23 (0.15–0.34) | 0.23 (0.14–0.35) | 0.20 (0.14–0.30) |  < 0.001 | ||
 ISSI2cp | 100.24 (70.43–142.99) | 121.26 (84.84–178.36) | 100.48 (73.23–138.89) | 96.67 (69.63–140.94) | 81.79 (60.18–116.89) |  < 0.001 |