Table 1 GENNID genetic and phenotypic characteristics by ethnic group (mean ± SD)
Characteristics | AA: African Americans | EA: European Americans | JA: Japanese Americans | MA: Mexican Americans |
|---|---|---|---|---|
# Subjects (# families) | 281 (73 families) | 516 (75 families) | 125 (15 families) | 598 (96 families) |
Median (min, max) # Subjects per family | 4 (1, 7) | 6 (1, 29) | 7 (3, 17) | 4 (1, 112) |
# QCa variants | 710,226 | 686,200 | 437,730 | 731,016 |
# Variants genotyped and imputed (association analysis) | 13,042,663 | 7,681,619 | 5,455,666 | 7,907,815 |
Age (years) | 52.4 ± 15.1 | 51.2 ± 16.8 | 56.1 ± 15.8 | 52.1 ± 15.8 |
Sex (% male) | 31.3% | 43.8% | 52% | 36.0% |
Self-reported diabetes status (% diabetes) | 51.2% | 37.2% | 27.20% | 47.7% |
Systolic blood pressure (SBP) (mmHg) | 128.5 ± 19.8 | 127.2 ± 19.1 | 121.8 ± 18.1 | 126.2 ± 19.3 |
Diastolic blood pressure (DBP) (mmHg) | 79.4 ± 10.8 | 78 ± 10.2 | 72.3 ± 11.5 | 74.6 ± 10.6 |
High density lipoproteins (HDL) (mg/dL) | 47.5 ± 12.3 | 40.5 ± 11.2 | 45.6 ± 14.2 | 39.4 ± 10.2 |
Triglycerides (TG), fasting (mg/dL) | 105.5 ± 110.3 | 143.8 ± 123.8 | 135.4 ± 104.5 | 160.9 ± 121.7 |
Glucose, fasting (mg/dL) | 146.8 ± 75.3 | 128.3 ± 56.7 | 115 ± 29.6 | 152.2 ± 76.9 |
Insulin, fasting (mg/dL) | 16.2 ± 21 | 11.5 ± 10.9 | 7.3 ± 6.3 | 17 ± 16.8 |
Weight (kg) | 86.8 ± 21.1 | 84.1 ± 20.4 | 65.7 ± 13.4 | 79 ± 17.7 |
Waist circumference (cm) | 98.5 ± 16 | 99.5 ± 16 | 88.7 ± 11.2 | 102.4 ± 14.3 |