Table 4 The correlation between serum asprosin concentrations and various parameters in T2DM patients
From: Increased serum asprosin is correlated with diabetic nephropathy
Parameters | Simple regression analysis | Multiple regression analysis | ||
|---|---|---|---|---|
R | P | β | P | |
Age (years) | 0.066 | 0.338 | ||
Gender (M/F) | 0.015 | 0.824 | ||
Duration (years) | 0.235 | 0.001 | 0.023 | 0.746 |
BMI (Kg/m2) | 0.034 | 0.619 | ||
SBP (mmHg) | 0.22 | 0.001 | 0.087 | 0.302 |
DBP (mmHg) | 0.07 | 0.31 | ||
HbA1c (%) | 0.065 | 0.35 | ||
TG (mmol/L) | 0.05 | 0.472 | ||
TC (mmol/L) | 0.043 | 0.533 | ||
HDL-C (mmol/L) | -0.007 | 0.917 | ||
LDL-C (mmol/L) | 0.032 | 0.644 | ||
BUN (nmol/L) | 0.404 | < 0.001 | 0.219 | 0.03 |
Cr (μmol/L) | 0.304 | < 0.001 | 0.159 | 0.158 |
UA (μmol/L) | 0.163 | 0.018 | 0.09 | 0.21 |
ACR (mg/g) | 0.466 | < 0.001 | 0.323 | < 0.001 |
GFR (mL/min/1.73 m2) | − 0.283 | < 0.001 | 0.078 | 0.356 |
Treatment | ||||
Metformin (n, %) | − 0.143 | 0.037 | − 0.009 | 0.907 |
Acarbose (n, %) | − 0.148 | 0.031 | − 0.08 | 0.282 |
Sulfonylureas (n, %) | − 0.121 | 0.078 | ||
DPP-IV inhibitor (n, %) | − 0.072 | 0.295 | ||
Insulin (n, %) | 0.079 | 0.255 | ||
Statin (n, %) | 0.009 | 0.897 | ||
CCB (n, %) | 0.163 | 0.018 | − 0.002 | 0.997 |
ACEI/ARB (n, %) | 0.23 | 0.001 | 0.069 | 0.423 |