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Table 3 Logistic regression analysis for determining the factors associated with DN

From: Increased serum asprosin is correlated with diabetic nephropathy

Characteristics

Univariate logistic regression

Multiple logistic regression

OR (95% CI)

P

OR (95% CI)

P

Age (years)

1.009 (0.986–1.031)

0.453

Gender (M/F)

1.147 (0.666–1.973)

0.622

Duration (years)

1.672 (1.404–1.991)

< 0.001

1.599 (1.318–1.941)

< 0.001

BMI (kg/m2)

0.997 (0.926–1.074)

0.94

SBP (mmHg)

1.022 (1.01–1.034)

< 0.001

1.012 (0.988–1.036)

0.332

DBP (mmHg)

1.024 (1.006–1.043)

0.011

1.008 (0.98–1.038)

0.572

HbA1c (%)

1.094 (0.898–1.333)

0.372

TG (mmol/L)

1.116 (0.9–1.384)

0.316

TC (mmol/L)

1.451 (1.104–1.907)

0.008

1.845 (0.581–5.861)

0.299

HDL-C (mmol/L)

1.782 (0.575–5.519)

0.317

LDL-C (mmol/L)

1.525 (1.098–2.118)

0.012

0.659 (0.163–2.668)

0.559

BUN (nmol/L)

1.326 (1.142–1.539)

< 0.001

1.301 (1.02–1.661)

0.034

Cr (μmol/L)

1.015 (1.004–1.026)

0.008

0.995 (0.974–1.016)

0.639

UA (μmol/L)

1.002 (0.999–1.005)

0.267

GFR (mL/min/1.73 m2)

0.991 (0.984–0.999)

0.028

1.005 (0.993–1.017)

0.397

Asprosin (ng/mL)

1.242 (1.142–1.35)

< 0.001

1.183 (1.064–1.315)

0.002

Treatment

 Metformin (n, %)

0.718 (0.398–1.295)

0.271

 Acarbose (n, %)

0.975 (0.567–1.677)

0.927

 Sulfonylureas (n, %)

0.919 (0.524–1.611)

0.769

 DPP-IV inhibitor (n, %)

0.794 (0.461–1.369)

0.407

 Insulin (n, %)

0.883 (0.505–1.544)

0.663

 Statin (n, %)

1.269 (0.737–2.186)

0.39

 CCB (n, %)

2.71 (1.507–4.874)

0.001

1.023 (0.382–2.736)

0.964

 ACEI/ARB (n, %)

3.056 (1.718–5.436)

< 0.001

1.348 (0.508–3.573)

0.549

  1. Abbreviation as Table 1