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Table 1 Demographic and clinical characteristics of children (commercial and Medicaid) with NASH, T2DM or both during 12 month baseline period (before matching)

From: Burden of non-alcoholic steatohepatitis among children with type 2 diabetes mellitus

 

NASH onlya,b

NASH + T2DMa,b

T2DM onlya

Odds Ratio (95% CI)

NASH + T2DM compared to NASH onlyc

Odds Ratio (95% CI)

NASH + T2DM compared to T2DM onlyc

Sample size, N

469

50

8074

  

Female, n (%)

166 (35)

29 (58)

4355 (54)

2.52 (1.39−4.56)

1.18 (0.67−2.07)

Age, mean (SD)

12.4 (3.2)

14.5 (2.5)

12.6 (4.0)

–

–

Age, median (IQR)

13 (5)

15 (2)

14 (5)

–

–

Age category, n (%)

 0–2

≤ 10

≤ 10

82 (1)

–

–

 3–4

≤ 10

≤ 10

369 (5)

–

–

 5–11

177 (38)

≤ 10

2069 (26)

–

–

 12–17

286 (61)

44 (88)

5554 (69)

4.69 (1.96−11.23)

3.33 (1.42−7.82)

Health Plan, n (%)

 Medicaid (N = 4514)

353 (75)

36 (72)

4125 (51)

0.85 (0.44−1.62)

2.46 (1.33−4.57)

 Commercial (N = 4079)

116 (25)

14 (28)

3949 (49)

1.18 (0.62−2.27)

0.41 (0.22−0.75)

Comorbidities at baseline, n (%)

 Obesity

308 (66)

37 (74)

2260 (28)

1.49 (0.77−2.88)

7.32 (3.88−13.80)

 Dyslipidemia

128 (27)

15 (30)

1022 (13)

1.14 (0.60−2.16)

2.96 (1.61−5.43)

 Systemic hypertension

28 (6)

14 (28)

806 (10)

6.13 (2.96−12.66)

3.51 (1.88−6.53)

  1. SD standard deviation, IQR interquartile range, CI confidence interval, NASH non-alcoholic steatohepatitis, T2DM type 2 diabetes mellitus
  2. aNASH was defined as a child having ≥ 1 claims ICD-10 diagnosis code in the inpatient or emergency department setting or ≥ 2 claims diagnosis codes in the outpatient setting. T2DM was defined as a child having ≥ 1 claims ICD-10 diagnosis code in the inpatient or emergency department setting or ≥ 2 claims diagnosis codes in the outpatient setting or evidence of dispensed antidiabetic medication (except metformin and insulin alone) or metformin fill with presence of T2DM diagnosis code or insulin fill only with presence of T2DM or DM NOS
  3. bCells containing ten or fewer children are masked due to privacy rules
  4. cBolded values are statistically significant at p < .05