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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Hesperidin alleviates insulin resistance by improving HG-induced oxidative stress and mitochondrial dysfunction by restoring miR-149

Fig. 3

Hesperidin attenuated insulin resistance in HG-treated LO2 cells. a The effect of hesperidin on the glucose content in the culture medium of HG-treated LO2 cells was examined. b The effects of hesperidin on the expression of GLUT2, GLUT4 and IRS1 were detected by qRT-PCR. c The effects of hesperidin on the phosphorylation of GSK3β, AKT and IRS1 were quantified by western blotting. All the data were presented as the mean ± S.D. *p < 0.05, **p < 0.01, *** p < 0.001

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