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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Hesperidin alleviates insulin resistance by improving HG-induced oxidative stress and mitochondrial dysfunction by restoring miR-149

Fig. 2

Hesperidin improved reduced oxidative stress and mitochondrial dysfunction in HG-treated LO2 cells. a The effect of hesperidin on ROS production was detected by a fluorescent MitoSox probe. b–d The effects of hesperidin on the levels of SOD, GPx and MDA were calculated by corresponding detection kits. e The effect of hesperidin on MMP was detected by JC-1 staining. f The effect of hesperidin on the ATP content was determined. All the data were presented as the mean ± S.D. *p < 0.05, **p < 0.01, *** p < 0.001

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