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Table 3 Change in variables from baseline at 3 months after Roux-en-Y gastric bypass (malabsorptive) and sleeve gastrectomy (restrictive) surgery

From: Improvements in cholesterol efflux capacity of HDL and adiponectin contribute to mitigation in cardiovascular disease risk after bariatric surgery in a cohort with morbid obesity

Variable

Sleeve gastrectomy (n = 14)

Roux-en-Y gastric bypass (n = 27)

Before surgery

After surgery

p

Before surgery

After surgery

p

BMI (kg/m2)

46.9 ± 10.1

39 ± 8.2

0.0001

44.8 ± 4.5

36.9 ± 3.9

0.0001

Glucose (mg/dl)

92.3 ± 22.2

94.5 ± 16

0.8

131.1 ± 37.1

104.1 ± 14.8

0.004

Insulin (mIU/l)

15.1 (11.8–21.8)

8.3 (4.3–12.0)

0.009

19.2 (12.8–27.6)

10.1 (7.5–14.3)

0.001

HOMA2- IR

2.3 (1.6–3.0)

1.2 (0.8–1.9)

0.12

3.1 (2.1–4.3)

1.5 (1.1–2.2)

0.0003

NEFA

0.73 ± 0.34

0.78 ± 0.2

0.57

0.8 ± 0.35

0.72 ± 0.33

0.47

ADIPO-IR

118.2 ± 80.2

92 ± 81.4

0.68

107.3 ± 77.6

51.8 ± 9.1

0.005

Hb1Ac

6.2 ± 1

5.3 ± 0.94

0.007

7.7 ± 2.0

6.2 ± 0.8

0.0007

Apo A-I (mg/dl)

117.5 ± 21.3

135.5 ± 25.7

0.06

103.5 ± 23.1

127.8 ± 18.6

0.006

Male

122.3 ± 32.1

133.5 ± 14.0

0.09

106.7 ± 13.1

123.3 ± 18.5

0.01

Female

111.3 ± 14.8

137.5 ± 28.2

0.04

102.8 ± 25.0

126.8 ± 19.0

0.002

Apo B (mg/dl)

87.8 ± 20.4

103.8 ± 19.1

0.02

75.4 ± 17.0

99.2 ± 16.5

0.001

TC (mg/dl)

193.2 ± 80.9

176.8 ± 34.6

0.35

163.1 ± 22.9

160.7 ± 22.6

0.66

HDL-C (mg/dl)

43.9 ± 11.1

42.3 ± 5.2

0.53

42.1 ± 9.3

37 ± 5.9

0.017

Male

41.7 ± 8.0

41.3 ± 5.0

0.92

39.3 ± 7.3

31.5 ± 4.2

0.03

Female

45.5 ± 12.7

42.6 ± 6.0

0.44

42.6 ± 9.7

38.2 ± 5.6

0.04

LDL-C (mg/dl)

103.5 ± 26.6

116.1 ± 33.0

0.12

99.5 ± 26.2

97.5 ± 29.4

0.74

TG (mg/dl)

146.9 ± 51.1

116.5 ± 36.9

0.009

137.6 ± 35.9

122.1 ± 48.7

0.14

VLDL-C (mg/dl)

26.6 ± 11.7

21.9 ± 8.7

0.16

24.6 ± 9.3

23.1 ± 9.6

0.5

CEC (A.U.)

0.89 ± 0.1

1.03 ± 0.18

0.012

0.92 ± 0.14

1.0 ± 0.14

0.006

Adiponectin (µg/ml)

6.0 ± 1.3

7.7 ± 1.5

0.001

5.4 ± 2.4

6.7 ± 2.7

0.02

Log resistin

2.4 ± 0.7

1.9 ± 0.67

0.06

2.3 ± 0.16

2.0 ± 0.78

0.09

Log MCP-1

1.6 ± 0.4

1.6 ± 0.47

0.97

1.9 ± 0.41

1.6 ± 0.53

0.08

IL-10 (pg/ml)

0.1 (0.01–0.44)

0.2 (0.12–0.56)

0.62

0.33 (0.1–0.8)

0.2 (0.11–0.54)

0.21

TNF-alpha (pg/ml)

2 ± 0.8

3 ± 1.4

0.05

2.5 ± 2.2

2.2 ± 1.3

0.6

  1. Data expressed as mean ± standard deviation or median (interquartile range)
  2. BMI body mass index, HOMA2-IR homeostatic model assessment method-insulin resistance, NEFA non-esterified fatty acids, Adipo-IR adipose tissue-insulin resistance, HbA1c glycated hemoglobin, Apo A-I apolipoprotein A-I, Apo B apolipoprotein B, TC total cholesterol, HDL-C high density lipoprotein-cholesterol, LDL-C low density lipoprotein-cholesterol, VLDL-C very low density lipoprotein-cholesterol, TG triglycerides, CEC cholesterol efflux capacity, MCP-1 monocyte chemoattractant protein-1, IL-10 interleukin 10, TNF-alpha tumor necrosis factor-alpha