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Table 3 Participants characteristics according to transient elastography results

From: Prevalence of non-alcoholic fatty liver disease and its associated factors in individuals with type 1 diabetes: a cross-sectional study in a tertiary care center in Brazil

 

Altered TE

Normal TE

p value

Demographical and clinical characteristics

N (%)

22 (23.2)

73 (76.8)

 

Age, years

40 ± 11

39 ± 14

0.625

Female gender, n (%)

11 (50.0)

44 (60.3)

0.392

Non-Caucasian, n (%)

9 (40.9)

39 (53.4)

0.303

Years of school attendance

12 ± 4

12 ± 3

0.833

Diabetes duration, years

22 ± 10

20 ± 9

0.448

BMI, kg/m2

28.9 ± 3.7

24.3 ± 3.6

 < 0.001

WC, cm

94.9 ± 11.3

83.2 ± 10.4

 < 0.001

HC, cm

104.5 ± 7.4

97.8 ± 7.0

 < 0.001

WHR

0.91 ± 0.08

0.85 ± 0.07

0.003

SBP, mmHg

135 ± 16

125 ± 16

0.011

DBP, mmHg

81 ± 11

76 ± 10

0.027

Insulin dose, U/kg

0.75 ± 0.26

0.77 ± 0.33

0.768

Hypertension, n (%)

14 (63.6)

29 (39.7)

0.048

Anti-hypertensive use, n (%)

13 (59.1)

26 (35.6)

0.050

Metformin use, n (%)

5 (22.7)

6 (8.2)

0.120

Statin use, n (%)

14 (63.6)

30 (41.1)

0.063

Acetylsalicylic acid use, n (%)

6 (27.3)

12 (16.4)

0.351

Currently smoking, n (%)

1 (4.5)

5 (5.3)

1.000

Metabolic syndrome, n (%)

15 (68.2)

27 (37.0)

0.010

FLI

60 [58]

13 [21]

 < 0.001

Laboratory measurements

HbA1c (%)

mmol/mol

8.9 [2.8]

74 [29]

8.5 [2.3]

70 [24]

0.717

FPG,mg/dl

130 [200]

116 [131]

0.517

Total cholesterol, mg/dl

170.0 [77.3]

161.0 [65.0]

0.880

HDL-c, mg/dl

50.8 [24.5]

47.6 [32.8]

0.880

LDL-c, mg/dl

99.9 [46.1]

91.4 [40.2]

0.383

Triglycerides, mg/dl

89.0 [99.0]

75.0 [62.5]

0.040

eGFR, ml/min/1.73 m2

99 [30]

100 [29]

0.771

Albumin, mg/dl

4.0 ± 0.7

4.0 ± 0.6

0.992

ALT, U/l

10.0 [8.5]

8.0 [7.0]

0.260

AST, U/l

14.5 [8.3]

12.0 [7.5]

0.082

GGT, mg/dl

20.5 [41.3]

19.0 [16.5]

0.596

CPK, mg/dl

119.0 [172.0]

80.0 [86.0]

0.667

CRP, mg/dl

0.3 [0.9]

0.2 [0.4]

0.771

Uric acid, mg/dl

3.8 [1.8]

3.5 [1.7]

0.383

  1. Altered TE refers to steatosis and/or fibrosis on transient elastography (TE). Data are represented as means ± standard deviation, median [interquartile range] or as numbers (percentages). BMI: body mass index; WC: waist circumference, HC: hip circumference; WHR: waist-to-hip ratio; SBP: systolic blood pressure, DBP: diastolic blood pressure; HbA1c: glycated hemoglobin; FPG: fasting plasma glucose; HDL: HDL cholesterol; LDL: LDL cholesterol; eGFR: estimated glomerular filtration rate by CKD-EPI equation; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase; CPK: creatine phosphokinase; CRP: C reactive protein; FLI: fatty liver index