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Table 2 Participants characteristics according to hepatic ultrasound results

From: Prevalence of non-alcoholic fatty liver disease and its associated factors in individuals with type 1 diabetes: a cross-sectional study in a tertiary care center in Brazil

 

Altered US

Normal US

p value

Demographical and clinical characteristics

N (%)

12 (12.6)

83 (87.4)

 

Age, years

40 ± 13

37 ± 13

0.459

Female gender, n (%)

9 (75.0)

46 (55.4)

0.199

Non-Caucasian, n (%)

8 (66.7)

40 (48.2)

0.232

Years of school attendance

11 ± 3

12 ± 3

0.383

Diabetes duration, years

19 ± 9

21 ± 10

0.406

BMI, kg/m2

26.7 ± 3.4

25.2 ± 4.1

0.209

WC, cm

89.7 ± 10.0

85.6 ± 11.8

0.253

HC, cm

100.0 ± 7.3

99.3 ± 7.7

0.759

WHR

0.90 ± 0.08

0.86 ± 0.08

0.135

SBP, mmHg

128 ± 18

127 ± 16

0.767

DBP, mmHg

76 ± 9

77 ± 11

0.668

Insulin dose, U/kg

0.82 ± 0.30

0.76 ± 0.31

0.499

Hypertension, n (%)

5 (41.7)

38 (45.8)

0.789

Anti-hypertensive use, n (%)

4 (33.3)

36 (43.4)

0.510

Metformin use, n (%)

2 (16.7)

9 (11.0)

0.567

Statin use, n (%)

5 (41.7)

40 (48.2)

0.672

Acetylsalicylic acid use, n (%)

2 (16.7)

16 (19.3)

0.829

Currently smoking, n (%)

2 (16.7)

4 (4.8)

0.165

Metabolic syndrome, n (%)

10 (83.3)

33 (39.8)

0.005

FLI

38 [43]

13 [35]

0.028

Laboratory measurements

HbA1c (%)

mmol/mol

8.6 [3.6]

70 [39]

8.6 [2.3]

70 [24]

0.757

FPG,mg/dl

116 [160]

160 [135]

0.728

Total cholesterol, mg/dl

154.5 [53.3]

167.0 [65.0]

0.787

HDL-c, mg/dl

38.1 [21.5]

50.0 [30.0]

0.034

LDL-c, mg/dl

83.6 [58.5]

94.8 [41.2]

0.375

Triglycerides, mg/dl

139.0 [190.8]

73.0 [60.8]

0.028

eGFR, ml/min/1.73 m2

107 [43]

99 [30]

0.728

Albumin, mg/dl

3.7 ± 0.6

4.0 ± 0.6

0.075

ALT, U/l

11.5 [15.3]

9.0 [7.0]

0.719

AST, U/l

15.5 [14.3]

13.0 [8.0]

0.507

GGT, mg/dl

18.5 [14.3]

19.0 [16.0]

0.848

CPK, mg/dl

100.5 [125.3]

81.0 [86.0]

0.670

CRP, mg/dl

0.4 [0.6]

0.2 [0.4]

0.334

Uric acid, mg/dl

3.6 [0.9]

3.6 [2.0]

0.848

  1. Altered US refers to steatosis on hepatic ultrasound. Data are represented as means ± standard deviation, median [interquartile range] or as numbers (percentages). BMI: body mass index; WC: waist circumference, HC: hip circumference; WHR: waist-to-hip ratio; SBP: systolic blood pressure, DBP: diastolic blood pressure; HbA1c: glycated hemoglobin; FPG: fasting plasma glucose; HDL: HDL cholesterol; LDL: LDL cholesterol; eGFR: estimated glomerular filtration rate by CKD-EPI equation; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase; CPK: creatine phosphokinase; CRP: C reactive protein; FLI: fatty liver index