Outcome | Â | Subgroup | Studies | Q statistic | I2(p-value) | Z | ES(95% CI) | Inter-group I2-P |
---|---|---|---|---|---|---|---|---|
TC | Total | 11 | 35.07 | 71.5(0.000) | 1.45(0.146) | − 4.36(− 10.24, 1.52) |  | |
Age |  < 52.8 years | 5 | 11.13 | 61.1(0.025) | 2.31(0.021) | − 11.54(− 21.32, − 1.75) | 0.072 | |
 > 52.8 years | 6 | 20.7 | 75.8(0.001) | 0.08(0.935) | − 0.31(− 7.66, 7.04) | |||
Dose |  < 1000 mg | 6 | 13.36 | 62.6(0.020) | 1.8(0.072) | − 8.88(− 18.57, 0.81) | 0.250 | |
 ≥ 1000 mg | 5 | 20.39 | 80.4(0.000) | 0.46(0.647) | − 1.73(− 9.12, 5.67) | |||
Duration |  ≤ 12 week | 6 | 13.56 | 63.1(0.019) | 1.22(0.222) | 5.1(− 3.09, 13.29) | 0.001 | |
 > 12 week | 5 | 10.93 | 63.4(0.027) | 3.35(0.001) | − 14.41(− 22.65, − 5.97) | |||
TG | Total | 10 | 63.02 | 85.7(0.000) | 2.09(0.036) | − 11.15(− 21.58, − 0.71) |  | |
Duration |  ≤ 12 week | 5 | 37.73 | 89.4(0.000) | 1.73(0.084) | 14(− 1.89, 29.90) | 0.000 | |
 > 12 week | 5 | 8.39 | 52.3(0.078) | 4.28(0.000) | − 30.19(− 44.02, − 16.36) | |||
Dose |  < 1000 mg | 5 | 54.82 | 92.7(0.000) | 0.66(0.509) | − 5.35(− 21.24, 10.53) | 0.343 | |
 ≥ 1000 mg | 5 | 7.30 | 45.2(0.121) | 2.20(0.028) | − 15.55(− 29.38, − 1.71) | |||
Age |  < 52.8 | 4 | 7.31 | 59(0.063) | 4.15(0.000) | − 39.66(− 58.38, − 20.95) | 0.000 | |
 > 52.8 | 6 | 42.77 | 88.3(0.000) | 0.27(0.789) | 1.71(− 10.86, 14.28) | |||
LDL | Total | 11 | 118.65 | 91.6(0.000) | 1.2(0.229) | 2.73(− 1.72, 7.17) |  | |
Dose |  < 1000 mg | 6 | 15.90 | 68.6(0.007) | 4.58(0.000) | − 17.77(− 25.37, − 10.17) | 0.000 | |
 ≥ 1000 mg | 5 | 60.34 | 93.4(0.000) | 4.78(0.000) | 13.35(7.88, 18.82) | |||
Duration |  ≤ 12 week | 6 | 40.03 | 87.5(0.000) | 6.04(0.000) | 18.2(12.3, 24.11) | 0.000 | |
 > 12 week | 5 | 17.82 | 77.5(0.001) | 5.07(0.000) | − 17.45(− 24.19, − 10.71) | |||
Age |  < 52.8 | 5 | 22.77 | 82.4(0.000) | 2.96(0.003) | − 12.98(− 21.57, − 4.40) | 0.000 | |
 > 52.8 | 6 | 78.33 | 93.6(0.000) | 3.2(0.001) | 8.46(3.27, 13.65) | |||
HDL | Total | 11 | 35.11 | 71.5(0.000) | 1.31(0.191) | 0.91(− 0.45, 2.27) |  | |
Dose |  < 1000 mg | 6 | 18.11 | 76.4(0.002) | 1.07(0.284) | 1.07(− 0.89, 3.02) | 0.822 | |
 ≥ 1000 mg | 5 | 16.95 | 72.4(0.003) | 0.78(0.434) | 0.76(− 1.14, 2.65) | |||
Duration |  ≤ 12 week | 6 | 8.32 | 39.9(0.139) | 1.54(0.122) | − 2.01(− 4.57, 0.54) | 0.008 | |
 > 12 week | 5 | 19.79 | 79.8(0.001) | 2.51(0.012) | 2.06(0.45, 3.67) | |||
Age |  < 52.8 | 5 | 16.19 | 75.3(0.003) | 2.94(0.003) | 3.53(1.18, 5.88) | 0.007 | |
 > 52.8 | 6 | 11.72 | 57.3(0.039) | 0.49(0.627) | − 0.41(− 2.08, 1.25) | |||
FBS | Total | 11 | 50.88 | 80.3(0.000) | 6.77(0.000) | − 16.94(− 21.84, − 12.04) |  | |
Dose |  < 1000 mg | 6 | 20.72 | 75.9(0.001) | 3.46(0.001) | − 17.49(− 27.39, − 7.59) | 0.900 | |
 ≥ 1000 mg | 5 | 30.4 | 86.7(0.000) | 5.82(0.000) | − 16.76(− 22.40, − 11.11) | |||
Duration |  ≤ 12 week | 6 | 5.03 | 0.61(0.412) | 1.12(0.246) | − 3.96(− 10.90, 2.98) | 0.000 | |
 > 12 week | 5 | 19.04 | 79.0(0.001) | 8.45(0.000) | − 29.86(− 36.79, − 22.93) | |||
Age |  < 52.8 | 5 | 20.71 | 80.7(0.000) | 8.34(0.000) | − 29.53(− 36.47, − 22.59) | 0.000 | |
 > 52.8 | 6 | 4.97 | 0.0(0.419) | 1.25(0.211) | − 4.41(− 11.34, 2.51) | |||
HgA1C | Total | 10 | 85.8 | 89.5(0.000) | 11.2(0.001) | − 1.01(− 1.18, − 0.83) |  | |
Dose |  < 1000 mg | 5 | 63.83 | 93.7(0.000) | 8.6(0.000) | − 1.62(− 1.99, − 1.25) | 0.000 | |
 ≥ 1000 mg | 5 | 8.32 | 51.9(0.081) | 8.15(0.000) | − 0.83(− 1.03, − 0.63) | |||
Duration |  ≤ 12 week | 5 | 12.17 | 67.1(0.016) | 7.38(0.000) | − 0.8(− 1.02, − 0.59) | 0.001 | |
 > 12 week | 5 | 62.87 | 93.6(0.000) | 9.11(0.000) | − 1.43(− 1.74, − 1.12) | |||
Age |  < 52.8 | 4 | 59.7 | 95(0.000) | 9.26(0.000) | − 1.47(− 1.78, − 1.16) |  | |
 > 52.8 | 6 | 13.65 | 63.4(0.018) | 7.31(0.000) | − 0.79(− 1.0, − 0.58) |