Fig. 6From: Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implicationsAirway hyperreactivity. The central insulin action is able to control airway reactivity, and in obesity central hyperinsulinemia induces an increased airway hyper-reactivity by stimulating airway-related pre-ganglionic parasympathetic fibers at the dorsal motor nucleus of the vagus (DMV) and nucleus ambiguous (NA), by the ERK signaling pathwayBack to article page